erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

References related to functions published in Others


PMIDJournalPublished DateAuthorTitle
21832242Am. J. Physiol., Cell Physiol.2011Yoo BK et al.Lysophosphatidic acid 5 receptor induces activation of Na(+)/H(+) exchanger 3 via apical epidermal growth factor receptor in intestinal epithelial cells.
7890608J. Biol. Chem.1995Koley AP et al.CO binding kinetics of human cytochrome P450 3A4. Specific interaction of substrates with kinetically distinguishable conformers.
7629141J. Biol. Chem.1995Quirós LM and Salas JABiosynthesis of the macrolide oleandomycin by Streptomyces antibioticus. Purification and kinetic characterization of an oleandomycin glucosyltransferase.
9422686Science1998Marsden AF et al.Engineering broader specificity into an antibiotic-producing polyketide synthase.
9066116FEMS Microbiol. Lett.1997Matsuoka M et al.A dyadic plasmid that shows MLS and PMS resistance in Staphylococcus aureus.
12044681FEMS Microbiol. Lett.2002Kim YH et al.Purification and characterization of an erythromycin esterase from an erythromycin-resistant Pseudomonas sp.
12235254J. Pharmacol. Exp. Ther.2002Milberg P et al.Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes.
12606769Mol. Pharmacol.2003Dinos GP et al.Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation.
10766792J. Biol. Chem.2000Quirós LM et al.Glycosylation of macrolide antibiotics. Purification and kinetic studies of a macrolide glycosyltransferase from Streptomyces antibioticus.
10866316Cancer Res.2000Quintieri L et al.In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
20876130Proc. Natl. Acad. Sci. U.S.A.2010Bulkley D et al.Revisiting the structures of several antibiotics bound to the bacterial ribosome.
21242274CMAJ2011Wright AJ et al.The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers.
20418422Appl. Environ. Microbiol.2010Useglio M et al.TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli.
18205815FEMS Microbiol. Ecol.2008Elevi Bardavid R and Oren ASensitivity of Haloquadratum and Salinibacter to antibiotics and other inhibitors: implications for the assessment of the contribution of Archaea and Bacteria to heterotrophic activities in hypersaline environments.
15870344Appl. Environ. Microbiol.2005Peirú S et al.Production of the potent antibacterial polyketide erythromycin C in Escherichia coli.
16514147Microbiology (Reading, Engl.)2006Rodríguez E et al.In vivo characterization of the dTDP-D-desosamine pathway of the megalomicin gene cluster from Micromonospora megalomicea.
17083011Clin. Infect. Dis.2006Kaplan EL et al.Reduced ability of penicillin to eradicate ingested group A streptococci from epithelial cells: clinical and pathogenetic implications.
17110371J. Biol. Chem.2007Sidhu AB et al.In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.
16651327Pediatrics2006Amer A and Fischer HAzithromycin does not cure pityriasis rosea.
21908288J. Vet. Diagn. Invest.2011Soehnlen MK et al.In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method.
23542952Am. J. Physiol. Lung Cell Mol. Physiol.2013Tarran R et al.Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion.