Avermectin A1a
Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.
References related to functions published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 10517585 | Microbiology (Reading, Engl.) | 1999 | Zhang YX et al. | Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production. |
| 21622528 | Microbiology (Reading, Engl.) | 2011 | Miyamoto KT et al. | The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis. |
| 23893108 | J. Bacteriol. | 2013 | Liu Y et al. | Characterization of SAV7471, a TetR-family transcriptional regulator involved in the regulation of coenzyme A metabolism in Streptomyces avermitilis. |
| 28285880 | Stem Cell Reports | 2017 | Brownjohn PW et al. | Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease. |
| 27895022 | Antimicrob. Agents Chemother. | 2017 | Mendes AM et al. | Inhibition of Plasmodium Liver Infection by Ivermectin. |
| 27249340 | Open Biol | 2016 | Chen LP et al. | Direct interaction of avermectin with epidermal growth factor receptor mediates the penetration resistance in Drosophila larvae. |
| 26638061 | Cell | 2015 | Shen B | A New Golden Age of Natural Products Drug Discovery. |