chrysin

chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
9177178	Proc. Natl. Acad. Sci. U.S.A.	1997	Critchfield JW et al.	Casein kinase II is a selective target of HIV-1 transcriptional inhibitors.
18434361	J. Endocrinol.	2008	Jana K et al.	Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.
15621053	Cardiovasc. Res.	2005	Woo AY et al.	Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism.
17237281	Mol. Cancer Ther.	2007	Fu B et al.	Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.
23888052	J. Biol. Chem.	2013	Liu H et al.	A chrysin derivative suppresses skin cancer growth by inhibiting cyclin-dependent kinases.
23125118	Microbiology (Reading, Engl.)	2013	Marin AM et al.	Naringenin degradation by the endophytic diazotroph Herbaspirillum seropedicae SmR1.
24169959	Cancer Prev Res (Phila)	2014	Liu H et al.	A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1.
20346967	Int. J. Biol. Macromol.	2010	Chinnam N et al.	Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner.
16781454	Free Radic. Biol. Med.	2006	Kachadourian R and Day BJ	Flavonoid-induced glutathione depletion: potential implications for cancer treatment.
27609609	Eur. J. Pharmacol.	2016	Filho CB et al.	Neurochemical factors associated with the antidepressant-like effect of flavonoid chrysin in chronically stressed mice.
26515162	Cancer Lett.	2016	Ronnekleiv-Kelly SM et al.	Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells.