Carvacrol

Carvacrol is a lipid of Prenol Lipids (PR) class. Carvacrol is associated with abnormalities such as Consumption-archaic term for TB, Disintegration (morphologic abnormality), Infection, Corn of toe and Candidiasis of vagina. The involved functions are known as Stereochemistry, Anabolism, Oxidation, Process and Binding (Molecular Function). Carvacrol often locates in Skin, Nerve Tissue, Membrane, Endothelium and Plasma membrane. The associated genes with Carvacrol are P4HTM gene, TRPV3 gene, TRPV1 gene, TRPV2 gene and TRPV4 gene. The related lipids are Fatty Acids, Lipopolysaccharides, Octanols, Micelles and butyrate.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
15258138	J. Biol. Chem.	2004	He X and de Montellano PR	Radical rebound mechanism in cytochrome P-450-catalyzed hydroxylation of the multifaceted radical clocks alpha- and beta-thujone.
14757239	FEMS Microbiol. Lett.	2004	Nostro A et al.	Susceptibility of methicillin-resistant staphylococci to oregano essential oil, carvacrol and thymol.
19578162	J. Lipid Res.	2010	Hotta M et al.	Carvacrol, a component of thyme oil, activates PPARalpha and gamma and suppresses COX-2 expression.
19429756	J. Med. Microbiol.	2009	Nostro A et al.	In vitro activity of carvacrol against staphylococcal preformed biofilm by liquid and vapour contact.
20086034	Mol. Pharmacol.	2010	Earley S et al.	A dietary agonist of transient receptor potential cation channel V3 elicits endothelium-dependent vasodilation.
17374894	J. Med. Microbiol.	2007	Nostro A et al.	Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms.
15456732	J. Antimicrob. Chemother.	2004	Chami F et al.	Evaluation of carvacrol and eugenol as prophylaxis and treatment of vaginal candidiasis in an immunosuppressed rat model.
22791718	J. Biol. Chem.	2012	Saito S et al.	Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates.
26453324	Am. J. Physiol. Heart Circ. Physiol.	2015	Pires PW et al.	Unitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.
24759772	Neuroscience	2014	Klein AH et al.	Eugenol and carvacrol excite first- and second-order trigeminal neurons and enhance their heat-evoked responses.
21131083	Int. J. Food Microbiol.	2011	de Oliveira TL et al.	Antimicrobial activity of Satureja montana L. essential oil against Clostridium perfringens type A inoculated in mortadella-type sausages formulated with different levels of sodium nitrite.
27075912	J. Nutr.	2016	Ran C et al.	Thymol and Carvacrol Affect Hybrid Tilapia through the Combination of Direct Stimulation and an Intestinal Microbiota-Mediated Effect: Insights from a Germ-Free Zebrafish Model.
26156773	Proc. Biol. Sci.	2015	Patricelli D et al.	Plant defences against ants provide a pathway to social parasitism in butterflies.
26146083	Cell Rep	2015	Peng G et al.	Plant-Derived Tick Repellents Activate the Honey Bee Ectoparasitic Mite TRPA1.
25338672	Mol. Pharmacol.	2015	Lansdell SJ et al.	Activation of human 5-hydroxytryptamine type 3 receptors via an allosteric transmembrane site.
24631628	Arch. Oral Biol.	2014	Zeidán-Chuliá F et al.	Focussed microarray analysis of apoptosis in periodontitis and its potential pharmacological targeting by carvacrol.