Ursolic acid is a lipid of Prenol Lipids (PR) class. Ursolic acid is associated with abnormalities such as Aortic Valve Insufficiency, Marles Greenberg Persaud syndrome, Infection, Arthritis and Dermatitis. The involved functions are known as Transcription, Genetic, Metabolic Inhibition, Cell physiology, Cell Differentiation process and Apoptosis. Ursolic acid often locates in Blood, Bacterial Fimbria, soluble, Extracellular and Microglial. The associated genes with ursolic acid are STAT3 gene, Genes, Reporter, IMPACT gene, ITSN2 gene and casamino acids. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Steroids, cholanic acid and 1-palmitoyl-2-oleoylphosphatidylethanolamine. The related experimental models are Mouse Model, Knock-out and Cancer Model.
PMID | Journal | Published Date | Author | Title |
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17855663 | Mol. Cancer Res. | 2007 | Pathak AK et al. | Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells. |
22551965 | Eur J Cardiothorac Surg | 2012 | Zeller I et al. | Inhibition of cell surface expression of endothelial adhesion molecules by ursolic acid prevents intimal hyperplasia of venous bypass grafts in rats. |
22869743 | Proc. Natl. Acad. Sci. U.S.A. | 2012 | Crown PL et al. | Ritual Black Drink consumption at Cahokia. |
22832932 | Clin. Cancer Res. | 2012 | Prasad S et al. | Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine. |
21586682 | Plant Cell | 2011 | Martin C et al. | How can research on plants contribute to promoting human health? |
26100520 | Cancer Prev Res (Phila) | 2015 | Cho J et al. | Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate. |
27063951 | J. Lipid Res. | 2016 | Leng S et al. | Ursolic acid enhances macrophage autophagy and attenuates atherogenesis. |
25861934 | Eur. J. Pharmacol. | 2015 | Colla AR et al. | Anxiolytic-like effects of ursolic acid in mice. |
25617694 | Eur J Med Chem | 2015 | Chen H et al. | Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents. |
25312987 | Biochim. Biophys. Acta | 2015 | Castro AJ et al. | The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance. |
24494201 | Redox Biol | 2014 | Ullevig SL et al. | Ursolic acid protects monocytes against metabolic stress-induced priming and dysfunction by preventing the induction of Nox4. |