Coenzyme Q10

Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
9012647	Arterioscler. Thromb. Vasc. Biol.	1997	de Rijke YB et al.	The redox status of coenzyme Q10 in total LDL as an indicator of in vivo oxidative modification. Studies on subjects with familial combined hyperlipidemia.
21297042	Cancer Epidemiol. Biomarkers Prev.	2011	Chai W et al.	Plasma coenzyme Q10 levels and prostate cancer risk: the multiethnic cohort study.
17412732	Brain	2007	Gempel K et al.	The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene.
16905642	Am. J. Epidemiol.	2006	de Lau LM et al.	Serum cholesterol levels and the risk of Parkinson's disease.
22513986	J. Nutr.	2012	Naidoo N et al.	Plasma vitamin E and coenzyme Q10 are not associated with a lower risk of acute myocardial infarction in Singapore Chinese adults.
23640862	Toxicol. Sci.	2013	Xue SY et al.	Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment.
23640978	Clin. Chem.	2013	Itkonen O et al.	Mitochondrial coenzyme Q10 determination by isotope-dilution liquid chromatography-tandem mass spectrometry.
23267110	Proc. Natl. Acad. Sci. U.S.A.	2013	Shi TJ et al.	Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model.
23018185	Biol. Reprod.	2012	Gendelman M and Roth Z	Incorporation of coenzyme Q10 into bovine oocytes improves mitochondrial features and alleviates the effects of summer thermal stress on developmental competence.
26522469	Am. J. Hum. Genet.	2015	Kishita Y et al.	Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.
26410779	Brain Res.	2015	Kaisar MA et al.	Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial?
25511910	J Trace Elem Med Biol	2015	Alehagen U and Aaseth J	Selenium and coenzyme Q10 interrelationship in cardiovascular diseases--A clinician's point of view.
25149567	Exp. Gerontol.	2014	Shetty RA et al.	Coenzyme Q10 and α-tocopherol reversed age-associated functional impairments in mice.
25034304	Mitochondrion	2014	Ma D et al.	Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10.
24775711	Neurobiol. Aging	2014	Sikorska M et al.	Nanomicellar formulation of coenzyme Q10 (Ubisol-Q10) effectively blocks ongoing neurodegeneration in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model: potential use as an adjuvant treatment in Parkinson's disease.