phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
12598499	Arch. Dis. Child. Fetal Neonatal Ed.	2003	Pereira SP et al.	Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding.
12843286	J. Neurosci.	2003	Li J et al.	Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons.
19321747	Proc. Natl. Acad. Sci. U.S.A.	2009	Widhalm JR et al.	A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.
19124480	Cancer Epidemiol. Biomarkers Prev.	2009	Nimptsch K et al.	Serum undercarboxylated osteocalcin as biomarker of vitamin K intake and risk of prostate cancer: a nested case-control study in the Heidelberg cohort of the European prospective investigation into cancer and nutrition.
20150517	J. Exp. Bot.	2010	Babujee L et al.	The proteome map of spinach leaf peroxisomes indicates partial compartmentalization of phylloquinone (vitamin K1) biosynthesis in plant peroxisomes.
17712007	Clin. Chem.	2007	Azharuddin MK et al.	HPLC method for plasma vitamin K1: effect of plasma triglyceride and acute-phase response on circulating concentrations.
18451262	Plant Physiol.	2008	Garcion C et al.	Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis.
18625626	Ann. Rheum. Dis.	2008	Neogi T et al.	Vitamin K in hand osteoarthritis: results from a randomised clinical trial.
22371323	J. Exp. Bot.	2012	Eugeni Piller L et al.	Plastid lipid droplets at the crossroads of prenylquinone metabolism.
22516723	Adv Nutr	2012	Shea MK and Holden RM	Vitamin K status and vascular calcification: evidence from observational and clinical studies.
22516726	Adv Nutr	2012	Shearer MJ et al.	Vitamin K nutrition, metabolism, and requirements: current concepts and future research.
23533172	Development	2013	Hegarty JM et al.	UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development.
25809266	Biophys. J.	2015	Santabarbara S et al.	Controlling electron transfer between the two cofactor chains of photosystem I by the redox state of one of their components.
25497998	Regul. Toxicol. Pharmacol.	2014	Davidson MH and Bechtel DH	Assessment of the effect of esterified propoxylated glycerol (EPG) on the status of fat-soluble vitamins and select water-soluble nutrients following dietary administration to humans for 8 weeks.
24929459	J Acupunct Meridian Stud	2014	Chao MT et al.	Increase in plasma phylloquinone concentrations following acupoint injection for the treatment of primary dysmenorrhea.