3-Methyl-2-oxobutanoic acid

3-Methyl-2-oxobutanoic acid is a lipid of Fatty Acyls (FA) class. 3-methyl-2-oxobutanoic acid is associated with abnormalities such as Maple Syrup Urine Disease and Kidney Failure, Chronic. The involved functions are known as Phosphorylation, Citric Acid Cycle, inhibitors, Process and Metabolic Control. 3-methyl-2-oxobutanoic acid often locates in Mitochondria, BL21, Cytoplasm, Ribosomes and Head. The associated genes with 3-Methyl-2-oxobutanoic acid are Genome, Homologous Gene, Operon, Alleles and Oxidoreductase Gene. The related lipids are dimyristoylphosphatidylglycerol, 9-oxononanoic acid, Valerates and alpha-ketocaproic acid.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
10839775	Clin. Chem.	2000	Pailla K et al.	Branched-chain keto-acids and pyruvate in blood: measurement by HPLC with fluorimetric detection and changes in older subjects.
15159544	Proc. Natl. Acad. Sci. U.S.A.	2004	Koon N et al.	Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis.
17329397	Am. J. Physiol., Cell Physiol.	2007	Schachter D	L-glutamine in vitro regulates rat aortic glutamate content and modulates nitric oxide formation and contractility responses.
16472748	Structure	2006	Machius M et al.	A versatile conformational switch regulates reactivity in human branched-chain alpha-ketoacid dehydrogenase.
15576032	Structure	2004	Wynn RM et al.	Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation.