4-Cholesten-3-one
4-Cholesten-3-one is a lipid of Sterol Lipids (ST) class. 4-cholesten-3-one is associated with abnormalities such as Dehydration, Xanthomatosis, Cerebrotendinous, Peripheral Neuropathy, L.mexicana and Xanthoma. The involved functions are known as CYP27A1activity, 25-hydroxycholesterol 7alpha-hydroxylase activity, Biochemical Pathway, Anabolism and Oxidation. 4-cholesten-3-one often locates in Mitochondria, Liver, Body tissue, Hepatic, Mitochondria and Endothelium of artery. The associated genes with 4-Cholesten-3-one are P4HTM gene, tryptones and Regulon. The related lipids are Cholestenones, 7-hydroxy-4-cholesten-3-one, cholest-4-en-3-one, 25-hydroxycholesterol and 24-hydroxycholesterol.
References related to functions published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 12777473 | J. Lipid Res. | 2003 | Norlin M et al. | On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation. |
| 22840389 | Phytochemistry | 2012 | Pan L et al. | Sterols with antileishmanial activity isolated from the roots of Pentalinon andrieuxii. |
| 21209222 | J. Neurosci. | 2011 | Martin LJ et al. | The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation. |
| 18492948 | J. Pharmacol. Exp. Ther. | 2008 | Bordet T et al. | Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy. |