lanosterol

lanosterol is a lipid of Sterol Lipids (ST) class. Lanosterol is associated with abnormalities such as Infection, Atherosclerosis, Myocardial Infarction, Chagas Disease and Fatty Liver. The involved functions are known as Signal, Cytokinesis, physiological aspects, Stereochemistry and ergosterol biosynthetic process. Lanosterol often locates in Body tissue, Membrane, Plasma membrane, Tissue membrane and Cytoskeletal Filaments. The associated genes with lanosterol are Retinoic Acid Response Element, P4HTM gene, CYP51A1 gene, HM13 gene and SC4MOL gene. The related lipids are pneumocysterol, Sterols, lanosteryl acetate, ebericol and cycloartenol. The related experimental models are Knock-out.

References related to functions published in Others

PMID	Journal	Published Date	Author	Title
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19897737	Eukaryotic Cell	2010	Joffrion TM et al.	Functional characterization and localization of Pneumocystis carinii lanosterol synthase.
17951521	Eukaryotic Cell	2007	Oliver BG et al.	cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p.
17885082	Plant Physiol.	2007	Chen Q et al.	Biosynthesis of phytosterol esters: identification of a sterol o-acyltransferase in Arabidopsis.
17585868	Arch. Biochem. Biophys.	2007	Lepesheva GI et al.	Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET.
16989930	Toxicology	2006	Trösken ER et al.	Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.
25746994	Appl. Environ. Microbiol.	2015	Price CL et al.	Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase.
24793591	J. Inorg. Biochem.	2014	Jennings GK et al.	Spin equilibrium and O₂-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine-threonine dyad.