clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
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10486356	Gut	1999	Matsuoka M et al.	Simultaneous colonisation of Helicobacter pylori with and without mutations in the 23S rRNA gene in patients with no history of clarithromycin exposure.
10548572	Clin. Diagn. Lab. Immunol.	1999	Woo PC et al.	Antibiotics modulate vaccine-induced humoral immune response.
11839700	Gut	2002	Owen RJ	Molecular testing for antibiotic resistance in Helicobacter pylori.
11408369	Drug Metab. Dispos.	2001	Bruce MA et al.	In vivo effect of clarithromycin on multiple cytochrome P450s.
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21690264	Drug Metab. Dispos.	2011	Peters J et al.	Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals.
21430235	Drug Metab. Dispos.	2011	König J et al.	Role of organic anion-transporting polypeptides for cellular mesalazine (5-aminosalicylic acid) uptake.
21395697	FEMS Immunol. Med. Microbiol.	2011	Hirao S et al.	Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.
20040578	J. Pharmacol. Exp. Ther.	2010	Yamaya M et al.	Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells.
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22123897	Pediatrics	2011	Ozdemir R et al.	Clarithromycin in preventing bronchopulmonary dysplasia in Ureaplasma urealyticum-positive preterm infants.
18441088	Cancer Res.	2008	Lee CW et al.	Helicobacter pylori eradication prevents progression of gastric cancer in hypergastrinemic INS-GAS mice.
16339220	BMJ	2006	Jespersen CM et al.	Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial.
16221754	Drug Metab. Dispos.	2006	Gurley BJ et al.	Effect of milk thistle (Silybum marianum) and black cohosh (Cimicifuga racemosa) supplementation on digoxin pharmacokinetics in humans.
15888466	J. Med. Microbiol.	2005	Elviss NC et al.	Helicobacter pylori antibiotic-resistance patterns and risk factors in adult dyspeptic patients from ethnically diverse populations in central and south London during 2000.
18650552	J. Dent. Res.	2008	Chou CH and Walters JD	Clarithromycin transport by gingival fibroblasts and epithelial cells.
18717637	J. Infect. Dis.	2008	Tagliabue C et al.	The impact of steroids given with macrolide therapy on experimental Mycoplasma pneumoniae respiratory infection.
22166485	Toxicol. Sci.	2012	Lin Z and Will Y	Evaluation of drugs with specific organ toxicities in organ-specific cell lines.
23801607	J. Infect. Dis.	2013	Lee HJ et al.	Eradication of Helicobacter pylori according to 23S ribosomal RNA point mutations associated with clarithromycin resistance.