NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
7890712	J. Biol. Chem.	1995	Gordon PB et al.	Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid.
9736650	J. Neurosci.	1998	Rundén E et al.	Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
11259346	Drug Metab. Dispos.	2001	Drewnowski A et al.	Genetic taste markers and food preferences.
12095991	J. Biol. Chem.	2002	Larsen AK et al.	Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes.
12840107	Mutagenesis	2003	Jagetia GC et al.	Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow.
19779132	J. Pharmacol. Exp. Ther.	2010	Shirasaka Y et al.	Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat.
20660284	J. Nutr.	2010	Demonty I et al.	The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women.
17846099	Chem. Senses	2008	Maehashi K et al.	Riboflavin-binding protein is a novel bitter inhibitor.
18755759	Mutagenesis	2008	Attia SM	Abatement by naringin of lomefloxacin-induced genomic instability in mice.
23172577	Eur J Orthod	2013	Nowak-Solinska E et al.	The effect of naringin on early growth and development of the spheno-occipital synchondrosis as measured by the expression of PTHrP and Sox9--an in vitro model.
19535679	Am. J. Physiol. Regul. Integr. Comp. Physiol.	2009	Little TJ et al.	Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans.