Glycyrrhetinic acid

Glycyrrhetinic acid is a lipid of Prenol Lipids (PR) class. Glycyrrhetinic acid is associated with abnormalities such as Congenital Abnormality, Cortisol 11-beta-ketoreductase deficiency, Hypertensive disease, Mineralocorticoid Excess Syndrome, Apparent and Syndrome. The involved functions are known as Signal, Muscle Contraction, Pressure- physical agent, Agent and Metabolic Inhibition. Glycyrrhetinic acid often locates in Protoplasm, Body tissue, Muscle, Connexon and Extracellular. The associated genes with Glycyrrhetinic acid are SLC33A1 gene, GJB1 gene, RNU1-1 gene, HADHA gene and RNU1-4 gene. The related lipids are Steroids, Saponin, Octanols, Heptanol and amyrin.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
9696712	Am. J. Physiol.	1998	Eugenín EA et al.	Gap junctional communication coordinates vasopressin-induced glycogenolysis in rat hepatocytes.
11259395	FASEB J.	2001	Oviedo-Orta E et al.	Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication.
11350956	J. Biol. Chem.	2001	Odermatt A et al.	The intracellular localization of the mineralocorticoid receptor is regulated by 11beta-hydroxysteroid dehydrogenase type 2.
11980696	Circulation	2002	Ferrari P	Endothelin 1 type a receptor antagonism prevents vascular dysfunction and hypertension induced by 11beta-hydroxysteroid dehydrogenase inhibition: role of nitric oxide.
12239243	J. Am. Soc. Nephrol.	2002	Ferrari P et al.	Modulation of renal calcium handling by 11 beta-hydroxysteroid dehydrogenase type 2.
11007814	Nephrol. Dial. Transplant.	2000	Frey FJ and Ferrari P	Pastis and hypertension--what is the molecular basis?
9683905	Cardiovasc. Res.	1998	van Uum SH et al.	The role of 11 beta-hydroxysteroid dehydrogenase in the pathogenesis of hypertension.
15319331	Drug Metab. Dispos.	2004	Breyer-Pfaff U et al.	Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
17581924	Am. J. Physiol. Renal Physiol.	2007	Ikeda Y et al.	Role of gap junctions in spontaneous activity of the rat bladder.
18401004	Am. J. Physiol. Regul. Integr. Comp. Physiol.	2008	Toma I et al.	Connexin 40 and ATP-dependent intercellular calcium wave in renal glomerular endothelial cells.
23114775	Antimicrob. Agents Chemother.	2013	Long DR et al.	18β-Glycyrrhetinic acid inhibits methicillin-resistant Staphylococcus aureus survival and attenuates virulence gene expression.