phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
References related to genes published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 12843286 | J. Neurosci. | 2003 | Li J et al. | Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. |
| 19321747 | Proc. Natl. Acad. Sci. U.S.A. | 2009 | Widhalm JR et al. | A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1. |
| 19124480 | Cancer Epidemiol. Biomarkers Prev. | 2009 | Nimptsch K et al. | Serum undercarboxylated osteocalcin as biomarker of vitamin K intake and risk of prostate cancer: a nested case-control study in the Heidelberg cohort of the European prospective investigation into cancer and nutrition. |
| 20150517 | J. Exp. Bot. | 2010 | Babujee L et al. | The proteome map of spinach leaf peroxisomes indicates partial compartmentalization of phylloquinone (vitamin K1) biosynthesis in plant peroxisomes. |
| 20167683 | Clin J Am Soc Nephrol | 2010 | Holden RM et al. | Vitamins K and D status in stages 3-5 chronic kidney disease. |
| 18451262 | Plant Physiol. | 2008 | Garcion C et al. | Characterization and biological function of the ISOCHORISMATE SYNTHASE2 gene of Arabidopsis. |
| 18625626 | Ann. Rheum. Dis. | 2008 | Neogi T et al. | Vitamin K in hand osteoarthritis: results from a randomised clinical trial. |
| 22371323 | J. Exp. Bot. | 2012 | Eugeni Piller L et al. | Plastid lipid droplets at the crossroads of prenylquinone metabolism. |
| 22516726 | Adv Nutr | 2012 | Shearer MJ et al. | Vitamin K nutrition, metabolism, and requirements: current concepts and future research. |
| 23533172 | Development | 2013 | Hegarty JM et al. | UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development. |