Sphinganine

Sphinganine is a lipid of Sphingolipids (SP) class. Sphinganine is associated with abnormalities such as Sphingolipidoses, CLEFT LIP, CONGENITAL HEALED, Aortic aneurysm, familial thoracic 4, Morphologically altered structure and Atherosclerosis. The involved functions are known as Transcription, Genetic, Signal, Muscle Contraction, biological adaptation to stress and Gene Expression. Sphinganine often locates in Tissue membrane, Membrane, Protoplasm, Plasma membrane and Cytoplasmic. The associated genes with Sphinganine are SLC33A1 gene, HM13 gene, P4HTM gene, SPHK1 gene and SPHK2 gene. The related lipids are Sphingolipids, Phosphatidylserines, Sterols, Fatty Acids and inositolphosphorylceramide. The related experimental models are Mouse Model and Knock-out.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
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11431347	Cancer Res.	2001	Wang H et al.	N-(4-hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase.
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18599698	Int. J. Syst. Evol. Microbiol.	2008	Matsuyama H et al.	Sphingobacterium kitahiroshimense sp. nov., isolated from soil.
22354293	Antimicrob. Agents Chemother.	2012	Vandenbosch D et al.	Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells.
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15665242	Plant Physiol.	2005	Coursol S et al.	Arabidopsis sphingosine kinase and the effects of phytosphingosine-1-phosphate on stomatal aperture.
26277409	Biochim. Biophys. Acta	2015	Megson ZA et al.	Inositol-phosphodihydroceramides in the periodontal pathogen Tannerella forsythia: Structural analysis and incorporation of exogenous myo-inositol.
26005054	Toxicol. Lett.	2015	Poulsen C et al.	Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells.