phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
11726514	EMBO J.	2001	Friant S et al.	Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast.
12576463	Clin. Cancer Res.	2003	Park MT et al.	Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.
20030721	FEMS Microbiol. Lett.	2010	Thevissen K et al.	Skn1 and Ipt1 negatively regulate autophagy in Saccharomyces cerevisiae.
15486061	Blood	2005	Park MT et al.	Phytosphingosine in combination with ionizing radiation enhances apoptotic cell death in radiation-resistant cancer cells through ROS-dependent and -independent AIF release.
16879426	FEMS Yeast Res.	2006	Yang Z et al.	Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast.
17237268	Mol. Cancer Ther.	2007	Park MT et al.	Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells.
27561298	J. Lipid Res.	2016	Martínez-Montañés F et al.	Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether.
15665242	Plant Physiol.	2005	Coursol S et al.	Arabidopsis sphingosine kinase and the effects of phytosphingosine-1-phosphate on stomatal aperture.
17070498	Biochim. Biophys. Acta	2006	Goñi FM and Alonso A	Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids.