22-Hydroxycholesterol
22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.
References related to genes published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 16371446 | J. Pharmacol. Exp. Ther. | 2006 | Deng R et al. | Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor. |
| 23110859 | Circulation | 2012 | Valbuena-Diez AC et al. | Oxysterol-induced soluble endoglin release and its involvement in hypertension. |
| 20227267 | Prostaglandins Leukot. Essent. Fatty Acids | 2010 Apr-Jun | Vallim T and Salter AM | Regulation of hepatic gene expression by saturated fatty acids. |
| 19581416 | Diabetes | 2009 | Cardellini M et al. | TIMP3 is reduced in atherosclerotic plaques from subjects with type 2 diabetes and increased by SirT1. |
| 12032171 | J. Lipid Res. | 2002 | Kaplan R et al. | Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway. |