phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to lipids published in Others

PMID	Journal	Published Date	Author	Title
26123195	J. Gen. Physiol.	2015	Badheka D et al.	Transient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel.
26038556	Proc. Natl. Acad. Sci. U.S.A.	2015	Wang H et al.	GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion.
25825728	Proc. Natl. Acad. Sci. U.S.A.	2015	Jeschke A et al.	Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.
25713054	FASEB J.	2015	Lacalle RA et al.	Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity.
25525797	Cell Host Microbe	2014	Roulin PS et al.	Rhinovirus uses a phosphatidylinositol 4-phosphate/cholesterol counter-current for the formation of replication compartments at the ER-Golgi interface.
25224012	Antimicrob. Agents Chemother.	2014	Reghellin V et al.	NS5A inhibitors impair NS5A-phosphatidylinositol 4-kinase IIIα complex formation and cause a decrease of phosphatidylinositol 4-phosphate and cholesterol levels in hepatitis C virus-associated membranes.
24530282	Structure	2014	Del Campo CM et al.	Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.
22722250	Science	2012	Hammond GR et al.	PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity.
21764313	Trends Cell Biol.	2011	Santiago-Tirado FH and Bretscher A	Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network.
19296914	Cell. Signal.	2009	Luo R et al.	Arf GAP2 is positively regulated by coatomer and cargo.
15657391	J. Cell Biol.	2005	Faulhammer F et al.	Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p.
1311174	Biochem. J.	1992	Roldan ER and Harrison RA	The role of diacylglycerol in the exocytosis of the sperm acrosome. Studies using diacylglycerol lipase and diacylglycerol kinase inhibitors and exogenous diacylglycerols.