22-Hydroxycholesterol

22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.

References related to lipids published in Others


PMIDJournalPublished DateAuthorTitle
23110859Circulation2012Valbuena-Diez AC et al.Oxysterol-induced soluble endoglin release and its involvement in hypertension.
15210833J. Pharmacol. Exp. Ther.2004Ando H et al.Effects of pravastatin on the expression of ATP-binding cassette transporter A1.
20227267Prostaglandins Leukot. Essent. Fatty Acids2010 Apr-JunVallim T and Salter AMRegulation of hepatic gene expression by saturated fatty acids.
17693624J. Lipid Res.2007Buono C et al.Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL.
12032171J. Lipid Res.2002Kaplan R et al.Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway.
27206966Biochim. Biophys. Acta2016Kim H et al.22(R)-hydroxycholesterol induces HuR-dependent MAP kinase phosphatase-1 expression via mGluR5-mediated Ca(2+)/PKCĪ± signaling.
26635040Haematologica2016Ceroi A et al.The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation.