26-Hydroxycholesterol

26-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 26-hydroxycholesterol is associated with abnormalities such as Cardiovascular Diseases, Vascular Diseases, Metabolic syndrome, Obesity and Fatty Streak, Arterial. The involved functions are known as Oxidation, phospholipase activity, glucose metabolism, Binding (Molecular Function) and Regulation. 26-hydroxycholesterol often locates in Immune system, Body tissue, Extracellular, Protoplasm and Back. The associated genes with 26-Hydroxycholesterol are Homologous Gene, chylomicron remnant, Receptor Gene, Alleles and D3 compound. The related lipids are 27-hydroxycholesterol, Hydroxycholesterols, Lysophosphatidylcholines, Total cholesterol and Lipopolysaccharides. The related experimental models are Knock-out and Transgenic Model.

References related to lipids published in Others

PMID	Journal	Published Date	Author	Title
20227267	Prostaglandins Leukot. Essent. Fatty Acids	2010 Apr-Jun	Vallim T and Salter AM	Regulation of hepatic gene expression by saturated fatty acids.
26563834	J. Steroid Biochem. Mol. Biol.	2016	Umetani M	Re-adopting classical nuclear receptors by cholesterol metabolites.
26381871	Arterioscler. Thromb. Vasc. Biol.	2015	Yin K et al.	Vitamin D Protects Against Atherosclerosis via Regulation of Cholesterol Efflux and Macrophage Polarization in Hypercholesterolemic Swine.
25497142	Biochim. Biophys. Acta	2015	Kim SM et al.	27-Hydroxycholesterol up-regulates CD14 and predisposes monocytic cells to superproduction of CCL2 in response to lipopolysaccharide.
25458418	Trends Endocrinol. Metab.	2014	Nelson ER et al.	Cholesterol and breast cancer pathophysiology.
25084324	Steroids	2014	Wardell SE et al.	From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).
25060521	Cancer Res.	2014	McDonnell DP et al.	Obesity, cholesterol metabolism, and breast cancer pathogenesis.
24954418	Cell Metab.	2014	Umetani M et al.	The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha.