7-Dehydrocholesterol

7-Dehydrocholesterol is a lipid of Sterol Lipids (ST) class. 7-dehydrocholesterol is associated with abnormalities such as Dehydration, Exanthema, RETINITIS PIGMENTOSA 49, Congenital Abnormality and Failure to Thrive. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Mutation, Lysis, Anabolism and Biosynthetic Pathways. 7-dehydrocholesterol often locates in Plasma membrane, Body tissue, Tissue membrane, Membrane and outer membrane. The associated genes with 7-Dehydrocholesterol are mutant gene, THEMIS gene, IGKV1D-37 gene, LGALS4 gene and Orthologous Gene. The related lipids are Membrane Lipids, Steroids, Sterols, campesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out and Rodent Model.

References related to lipids published in Others

PMID	Journal	Published Date	Author	Title
20501590	Development	2010	Niwa R et al.	Non-molting glossy/shroud encodes a short-chain dehydrogenase/reductase that functions in the 'Black Box' of the ecdysteroid biosynthesis pathway.
20558592	Mol. Pharmacol.	2010	Lauth M et al.	Antipsychotic drugs regulate hedgehog signaling by modulation of 7-dehydrocholesterol reductase levels.
23144252	J. Bacteriol.	2013	Shimomura H et al.	Detoxification of 7-dehydrocholesterol fatal to Helicobacter pylori is a novel role of cholesterol glucosylation.
22106170	Drug Metab. Dispos.	2012	Tuckey RC et al.	Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.
20153720	Biochim. Biophys. Acta	2010	Cui ZK et al.	Influence of the nature of the sterol on the behavior of palmitic acid/sterol mixtures and their derived liposomes.
20018479	J. Autoimmun.	2010	Maverakis E et al.	Light, including ultraviolet.
17008445	Development	2006	Bijlsma MF et al.	A dual role for 7-dehydrocholesterol reductase in regulating Hedgehog signalling?
12070263	J. Med. Genet.	2002	Waye JS et al.	Smith-Lemli-Opitz syndrome: carrier frequency and spectrum of DHCR7 mutations in Canada.
11901095	Drug Metab. Dispos.	2002	Kitamura S et al.	Reductive metabolism of an alpha,beta-ketoalkyne, 4-phenyl-3-butyn-2-one, by rat liver preparations.
27162362	Proc. Natl. Acad. Sci. U.S.A.	2016	Sever N et al.	Endogenous B-ring oxysterols inhibit the Hedgehog component Smoothened in a manner distinct from cyclopamine or side-chain oxysterols.
26214382	J. Invest. Dermatol.	2015	Xue Y et al.	Androgens Attenuate Vitamin D Production Induced by UVB Irradiation of the Skin of Male Mice by an Enzymatic Mechanism.