Ecdysone

Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.

References related to lipids published in Others


PMIDJournalPublished DateAuthorTitle
15107428J. Biol. Chem.2004Kumar MB et al.Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists.
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15026367Cancer Res.2004Kim HS et al.Insulin-like growth factor-binding protein 3 induces caspase-dependent apoptosis through a death receptor-mediated pathway in MCF-7 human breast cancer cells.
22751499Genes Dev.2012Jin H et al.Conserved microRNA miR-8 controls body size in response to steroid signaling in Drosophila.
23197702J. Neurosci.2012Loncle N and Williams DWAn interaction screen identifies headcase as a regulator of large-scale pruning.
12963111Mech. Dev.2003Schubiger M et al.Isoform specific control of gene activity in vivo by the Drosophila ecdysone receptor.
12721294J. Biol. Chem.2003Yamada R and Sonobe HPurification, kinetic characterization, and molecular cloning of a novel enzyme ecdysteroid-phosphate phosphatase.
15809296J. Biol. Chem.2005Carmichael JA et al.The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.
11703937Dev. Cell2001Thummel CSMolecular mechanisms of developmental timing in C. elegans and Drosophila.
27326933Dev. Cell2016Danielsen ET et al.A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing.
26773159J. Immunol.2016Sun W et al.Ecdysone Titer Determined by 3DE-3β-Reductase Enhances the Immune Response in the Silkworm.
26721418Dev. Biol.2016Valzania L et al.Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis.
25959239Dev. Biol.2015Borsos BN et al.Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis.