Cholic acid
Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.
References related to lipids published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 10037814 | Nucleic Acids Res. | 1999 | Wu L and Curran JF | An allosteric synthetic DNA. |
| 12970144 | Gut | 2003 | Lemonde HA et al. | Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy. |
| 10756198 | Nucleic Acids Res. | 2000 | Kato T et al. | Interaction of three-way DNA junctions with steroids. |
| 16461384 | Plant Physiol. | 2006 | Koga J et al. | Cholic acid, a bile acid elicitor of hypersensitive cell death, pathogenesis-related protein synthesis, and phytoalexin accumulation in rice. |
| 16123326 | Arterioscler. Thromb. Vasc. Biol. | 2005 | Masson D et al. | Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profile. |
| 18539741 | J. Bacteriol. | 2008 | Horinouchi M et al. | Identification of genes involved in inversion of stereochemistry of a C-12 hydroxyl group in the catabolism of cholic acid by Comamonas testosteroni TA441. |
| 18583509 | Drug Metab. Dispos. | 2008 | Deo AK and Bandiera SM | Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. |
| 25034404 | J. Pharmacol. Exp. Ther. | 2014 | Cheng X et al. | Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum. |
| 22096226 | Mol. Pharmacol. | 2012 | Blazquez AG et al. | Characterization of the role of ABCG2 as a bile acid transporter in liver and placenta. |
| 25477283 | FASEB J. | 2015 | Shih DM et al. | PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. |