(e,e,e,e)-squalene
(e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids.
References related to lipids published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11226224 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Shibata N et al. | Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. |
| 11369807 | J. Lipid Res. | 2001 | Relas H et al. | Fate of intravenously administered squalene and plant sterols in human subjects. |
| 12226513 | Plant Physiol. | 2002 | Wentzinger LF et al. | Inhibition of squalene synthase and squalene epoxidase in tobacco cells triggers an up-regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase. |
| 19834104 | Arterioscler. Thromb. Vasc. Biol. | 2010 | van Himbergen TM et al. | Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway. |
| 16484558 | J. Nutr. | 2006 | Singh DK and Porter TD | Inhibition of sterol 4alpha-methyl oxidase is the principal mechanism by which garlic decreases cholesterol synthesis. |