erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

References related to locations published in Others


PMIDJournalPublished DateAuthorTitle
7629141J. Biol. Chem.1995QuirĂ³s LM and Salas JABiosynthesis of the macrolide oleandomycin by Streptomyces antibioticus. Purification and kinetic characterization of an oleandomycin glucosyltransferase.
9806945Drug Metab. Dispos.1998Yamazaki H and Shimada TComparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
11577156Microbiology (Reading, Engl.)2001Korycka-Machala M et al.Polycations increase the permeability of Mycobacterium vaccae cell envelopes to hydrophobic compounds.
12814973Drug Metab. Dispos.2003Ito K et al.Prediction of the in vivo interaction between midazolam and macrolides based on in vitro studies using human liver microsomes.
12606769Mol. Pharmacol.2003Dinos GP et al.Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation.
10866316Cancer Res.2000Quintieri L et al.In vivo antitumor activity and host toxicity of methoxymorpholinyl doxorubicin: role of cytochrome P450 3A.
20876130Proc. Natl. Acad. Sci. U.S.A.2010Bulkley D et al.Revisiting the structures of several antibiotics bound to the bacterial ribosome.
17083011Clin. Infect. Dis.2006Kaplan EL et al.Reduced ability of penicillin to eradicate ingested group A streptococci from epithelial cells: clinical and pathogenetic implications.
17110371J. Biol. Chem.2007Sidhu AB et al.In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.
16575736Clin. Infect. Dis.2006Gagliotti C et al.Macrolide prescriptions and erythromycin resistance of Streptococcus pyogenes.
23542952Am. J. Physiol. Lung Cell Mol. Physiol.2013Tarran R et al.Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion.