clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
PMID | Journal | Published Date | Author | Title |
---|---|---|---|---|
10395860 | J. Infect. Dis. | 1999 | Hafner R et al. | Correlation of quantitative bone marrow and blood cultures in AIDS patients with disseminated Mycobacterium avium complex infection. |
9605144 | J. Immunol. | 1998 | Doherty TM and Sher A | IL-12 promotes drug-induced clearance of Mycobacterium avium infection in mice. |
10075942 | Gut | 1999 | Owen RJ | Helicobacter pylori resists arrest. |
10075951 | Gut | 1999 | Marais A et al. | Direct detection of Helicobacter pylori resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens. |
10548572 | Clin. Diagn. Lab. Immunol. | 1999 | Woo PC et al. | Antibiotics modulate vaccine-induced humoral immune response. |
11463936 | Sex Transm Infect | 2001 | Prime K and French P | Neuropsychiatric reaction induced by clarithromycin in a patient on highly active antiretroviral therapy (HAART). |
11477184 | Nephrol. Dial. Transplant. | 2001 | Verhelst D et al. | Purple-blue subcutaneous nodules after renal transplantation: not always Kaposi sarcoma. |
11408369 | Drug Metab. Dispos. | 2001 | Bruce MA et al. | In vivo effect of clarithromycin on multiple cytochrome P450s. |
12065733 | J. Pharmacol. Exp. Ther. | 2002 | Volberg WA et al. | Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics. |
12235069 | Gut | 2002 | Sherwood PV et al. | Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats. |
12818892 | Am. J. Physiol. Lung Cell Mol. Physiol. | 2003 | Kaneko Y et al. | Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis. |
12853380 | Clin. Diagn. Lab. Immunol. | 2003 | Berg HF et al. | Effect of clarithromycin on inflammatory markers in patients with atherosclerosis. |
10764702 | Gut | 2000 | Trebesius K et al. | Rapid and specific detection of Helicobacter pylori macrolide resistance in gastric tissue by fluorescent in situ hybridisation. |
11063500 | Clin. Diagn. Lab. Immunol. | 2000 | Chow LW et al. | Clarithromycin attenuates mastectomy-induced acute inflammatory response. |
10950845 | Drug Metab. Dispos. | 2000 | Mayhew BS et al. | An in vitro model for predicting in vivo inhibition of cytochrome P450 3A4 by metabolic intermediate complex formation. |
10671330 | Clin. Infect. Dis. | 2000 | Griffith DE et al. | Early results (at 6 months) with intermittent clarithromycin-including regimens for lung disease due to Mycobacterium avium complex. |
15306603 | Gut | 2004 | Mégraud F | H pylori antibiotic resistance: prevalence, importance, and advances in testing. |
15342952 | Toxicol. Sci. | 2005 | Sawada H et al. | A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system. |
21148526 | Clin. Infect. Dis. | 2011 | Chauty A et al. | Oral treatment for Mycobacterium ulcerans infection: results from a pilot study in Benin. |
21690264 | Drug Metab. Dispos. | 2011 | Peters J et al. | Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals. |
19884323 | Drug Metab. Dispos. | 2010 | Quinney SK et al. | Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin. |
20093375 | J. Med. Microbiol. | 2010 | De Francesco V et al. | Helicobacter pylori antibiotic resistance and [13C]urea breath test values. |
20040578 | J. Pharmacol. Exp. Ther. | 2010 | Yamaya M et al. | Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells. |
20847136 | Drug Metab. Dispos. | 2010 | Brown HS et al. | Comparative use of isolated hepatocytes and hepatic microsomes for cytochrome P450 inhibition studies: transporter-enzyme interplay. |
22123897 | Pediatrics | 2011 | Ozdemir R et al. | Clarithromycin in preventing bronchopulmonary dysplasia in Ureaplasma urealyticum-positive preterm infants. |
17893176 | J. Med. Microbiol. | 2007 | Moder KA et al. | Rapid screening of clarithromycin resistance in Helicobacter pylori by pyrosequencing. |
18422455 | J. Infect. Dis. | 2008 | Bermudez LE et al. | The efficacy of clarithromycin and the bicyclolide EDP-420 against Mycobacterium avium in a mouse model of pulmonary infection. |
15572537 | Eur. Respir. J. | 2004 | Lode H et al. | Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free interval. |
16007523 | Clin. Infect. Dis. | 2005 | Hung IF et al. | Fatal interaction between clarithromycin and colchicine in patients with renal insufficiency: a retrospective study. |
17050564 | Eur. Respir. J. | 2007 | Tahan F et al. | Clarithromycin in the treatment of RSV bronchiolitis: a double-blind, randomised, placebo-controlled trial. |
16946100 | Eur. Respir. J. | 2006 | Vicente de Vera C et al. | Delirium induced by clarithromycin in a patient with community-acquired pneumonia. |
18444850 | Clin. Infect. Dis. | 2008 | Giamarellos-Bourboulis EJ et al. | Effect of clarithromycin in patients with sepsis and ventilator-associated pneumonia. |
18650552 | J. Dent. Res. | 2008 | Chou CH and Walters JD | Clarithromycin transport by gingival fibroblasts and epithelial cells. |
22763637 | Clin. Microbiol. Rev. | 2012 | Brown-Elliott BA et al. | Antimicrobial susceptibility testing, drug resistance mechanisms, and therapy of infections with nontuberculous mycobacteria. |
22896605 | J. Virol. | 2012 | Takahashi E et al. | Oral clarithromycin enhances airway immunoglobulin A (IgA) immunity through induction of IgA class switching recombination and B-cell-activating factor of the tumor necrosis factor family molecule on mucosal dendritic cells in mice infected with influenza A virus. |
23801607 | J. Infect. Dis. | 2013 | Lee HJ et al. | Eradication of Helicobacter pylori according to 23S ribosomal RNA point mutations associated with clarithromycin resistance. |