nystatin

nystatin is a lipid of Polyketides (PK) class. Nystatin is associated with abnormalities such as Virus Diseases, Infection, Candidiasis, Leukopenia and Mycoses. The involved functions are known as Membrane Potentials, Uptake, Flow or discharge, Cell membrane potential and adenine transport. Nystatin often locates in Cell Wall, Plasma membrane, Extracellular, Membrane and Virion. The associated genes with nystatin are Genome, Integral Membrane Proteins, Amino Acids, Basic, P4HTM gene and Homologous Gene. The related lipids are Sterols, Liposomes, Membrane Lipids, Sphingolipids and 1,2-oleoylphosphatidylcholine. The related experimental models are Knock-out and Xenograft Model.

References related to locations published in Others

PMID	Journal	Published Date	Author	Title
9435506	Am. J. Physiol.	1997	Hillyard SD et al.	K+ transport and capacitance of the basolateral membrane of the larval frog skin.
9191571	Clin. Chem.	1997	van Norren K et al.	Comparison of methods for measurement of Na+/U+ countertransport across the erythrocyte membrane.
9374649	Am. J. Physiol.	1997	Liedtke CM and Cole T	Antisense oligodeoxynucleotide to PKC-delta blocks alpha 1-adrenergic activation of Na-K-2Cl cotransport.
8978281	Blood	1997	Cheung JY et al.	Modulation of calcium channels in human erythroblasts by erythropoietin.
10518038	FEMS Immunol. Med. Microbiol.	1999	Bujdáková H et al.	The influence of subinhibitory concentrations of conventional and experimental antifungal drugs on the expression of the iC3b binding protein in Candida albicans strains during filamentation.
10474196	FEMS Microbiol. Lett.	1999	Sekurova O et al.	Molecular cloning and analysis of a pleiotropic regulatory gene locus from the nystatin producer Streptomyces noursei ATCC11455.
10444632	J. Appl. Physiol.	1999	Waters CM et al.	Mechanical stretching of alveolar epithelial cells increases Na(+)-K(+)-ATPase activity.
9841493	Am. J. Physiol.	1998	Gaudio KM et al.	Role of heat stress response in the tolerance of immature renal tubules to anoxia.
11592939	Am. J. Physiol. Renal Physiol.	2001	Ortiz PA et al.	NO decreases thick ascending limb chloride absorption by reducing Na(+)-K(+)-2Cl(-) cotransporter activity.
11698247	Am. J. Physiol., Cell Physiol.	2001	Loffing-Cueni D et al.	Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line.
11880289	Am. J. Physiol. Lung Cell Mol. Physiol.	2002	Lazrak A et al.	cAMP regulation of Cl(-) and HCO(-)(3) secretion across rat fetal distal lung epithelial cells.
11893760	J. Exp. Biol.	2002	Zeiske W et al.	Insect midgut K(+) secretion: concerted run-down of apical/basolateral transporters with extra-/intracellular acidity.
11356731	Fam Pract	2001	Santelmann H et al.	Effectiveness of nystatin in polysymptomatic patients. A randomized, double-blind trial with nystatin versus placebo in general practice.
12149231	Blood	2002	Iwabuchi K and Nagaoka I	Lactosylceramide-enriched glycosphingolipid signaling domain mediates superoxide generation from human neutrophils.
11704561	Am. J. Physiol. Renal Physiol.	2001	Ren Y et al.	Nystatin and valinomycin induce tubuloglomerular feedback.
12011010	Infect. Immun.	2002	Wasylnka JA and Moore MM	Uptake of Aspergillus fumigatus Conidia by phagocytic and nonphagocytic cells in vitro: quantitation using strains expressing green fluorescent protein.
12045230	J. Cell. Sci.	2002	Triantafilou M et al.	Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation.
12640041	J. Cell. Sci.	2003	Wasylnka JA and Moore MM	Aspergillus fumigatus conidia survive and germinate in acidic organelles of A549 epithelial cells.
12552000	J. Virol.	2003	Gilbert JM et al.	Cell penetration and trafficking of polyomavirus.
12857856	Mol. Biol. Cell	2003	Vinciguerra M et al.	Intracellular Na+ controls cell surface expression of Na,K-ATPase via a cAMP-independent PKA pathway in mammalian kidney collecting duct cells.
10640318	J. Pharmacol. Exp. Ther.	2000	Singh AK et al.	Stimulation of Cl(-) secretion by chlorzoxazone.
11071915	Mol. Biol. Cell	2000	Ricci V et al.	High cell sensitivity to Helicobacter pylori VacA toxin depends on a GPI-anchored protein and is not blocked by inhibition of the clathrin-mediated pathway of endocytosis.
10690319	Cardiovasc. Res.	1999	Mishra SK and Aaronson PI	A role for a glibenclamide-sensitive, relatively ATP-insensitive K+ current in regulating membrane potential and current in rat aorta.
9458841	Am. J. Physiol.	1998	Lavelle JP et al.	Disruption of guinea pig urinary bladder permeability barrier in noninfectious cystitis.
12186914	J. Virol.	2002	Stuart AD et al.	A novel cell entry pathway for a DAF-using human enterovirus is dependent on lipid rafts.
15192147	Proc. Natl. Acad. Sci. U.S.A.	2004	Kadota I et al.	A unified approach to polyene macrolides: synthesis of candidin and nystatin polyols.
14573803	J. Gen. Virol.	2003	Katzman RB and Longnecker R	Cholesterol-dependent infection of Burkitt's lymphoma cell lines by Epstein-Barr virus.
15282274	J. Neurosci.	2004	Fortin DL et al.	Lipid rafts mediate the synaptic localization of alpha-synuclein.
15196575	FEMS Immunol. Med. Microbiol.	2004	Khan MA et al.	Co-administration of immunomodulator tuftsin and liposomised nystatin can combat less susceptible Candida albicans infection in temporarily neutropenic mice.
15150117	Cancer Res.	2004	Lacour S et al.	Cisplatin-induced CD95 redistribution into membrane lipid rafts of HT29 human colon cancer cells.
21123756	Am. J. Physiol. Regul. Integr. Comp. Physiol.	2011	Berger J et al.	Evidence for basolateral Cl- channels as modulators of apical Cl- secretion in pulmonary epithelia of Xenopus laevis.
21482707	Blood	2011	Chen Y et al.	Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways.
21209359	Am. J. Physiol., Cell Physiol.	2011	Stewart AK et al.	Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.
19509228	Cancer Res.	2009	Migalovich HS et al.	Harnessing competing endocytic pathways for overcoming the tumor-blood barrier: magnetic resonance imaging and near-infrared imaging of bifunctional contrast media.
19385994	FEMS Immunol. Med. Microbiol.	2009	Lamberti Y et al.	Cholesterol-dependent attachment of human respiratory cells by Bordetella pertussis.
19843586	J. Cell. Sci.	2009	Kang YS et al.	Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway.
18310029	Microbiology (Reading, Engl.)	2008	Iwaki T et al.	Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe.
16394077	J. Neurophysiol.	2006	Koyama S and Appel SB	Characterization of M-current in ventral tegmental area dopamine neurons.
16361359	Am. J. Physiol. Lung Cell Mol. Physiol.	2006	Yumoto R et al.	Clathrin-mediated endocytosis of FITC-albumin in alveolar type II epithelial cell line RLE-6TN.
14973031	J. Bacteriol.	2004	Sekurova ON et al.	In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.
15528348	J. Immunol.	2004	Meyer zum Bueschenfelde CO et al.	Regulated recruitment of MHC class II and costimulatory molecules to lipid rafts in dendritic cells.
17139247	EMBO J.	2006	Blot V and McGraw TE	GLUT4 is internalized by a cholesterol-dependent nystatin-sensitive mechanism inhibited by insulin.
17108132	Cancer Res.	2006	Holzer AK and Howell SB	The internalization and degradation of human copper transporter 1 following cisplatin exposure.
16614374	Am. J. Physiol. Gastrointest. Liver Physiol.	2007	Tobey NA et al.	Effect of luminal acidity on the apical cation channel in rabbit esophageal epithelium.
16816005	Pediatrics	2006	Klein KC and Blackwood RA	Topical voriconazole solution for cutaneous aspergillosis in a pediatric patient after bone marrow transplant.
18687808	Mol. Pharmacol.	2008	Yin X et al.	Differential signaling pathways in angiotensin II- and epidermal growth factor-stimulated hepatic C9 cells.
18753224	J. Gen. Virol.	2008	Van Hamme E et al.	Clathrin- and caveolae-independent entry of feline infectious peritonitis virus in monocytes depends on dynamin.
22612788	FEMS Immunol. Med. Microbiol.	2012	Khan MA et al.	Immune stimulating and therapeutic potential of tuftsin-incorporated nystatin liposomes against Cryptococcus neoformans in leukopenic BALB/C mice.
22714405	Genetics	2012	Gerstein AC et al.	Parallel genetic changes and nonparallel gene-environment interactions characterize the evolution of drug resistance in yeast.
23054913	Biol. Lett.	2013	Gerstein AC	Mutational effects depend on ploidy level: all else is not equal.
23698302	J. Virol.	2013	Tugizov SM et al.	Epstein-Barr virus transcytosis through polarized oral epithelial cells.
25223717	Biochim. Biophys. Acta	2015	Chulkov EG et al.	Membrane dipole modifiers modulate single-length nystatin channels via reducing elastic stress in the vicinity of the lipid mouth of a pore.
26765097	Environ. Res.	2016	Clark RS et al.	Validation of research trajectory 1 of an Exposome framework: Exposure to benzo(a)pyrene confers enhanced susceptibility to bacterial infection.