LTD4
Ltd4 is a lipid of Fatty Acyls (FA) class. Ltd4 is associated with abnormalities such as Inflammatory Bowel Diseases, Inflammatory disorder, Asthma, Pneumonia and Allergic asthma. The involved functions are known as inhibitors, Signal Transduction, Cell Survival, antagonists and Phosphorylation. Ltd4 often locates in Membrane, Tissue membrane, Protoplasm, Cytoplasmic matrix and membrane fraction. The associated genes with LTD4 are ALOX5 gene, UMOD gene, P4HTM gene, RAF1 gene and Homologous Gene. The related lipids are Lipopolysaccharides.
References related to locations published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11369634 | Blood | 2001 | Bautz F et al. | Chemotaxis and transendothelial migration of CD34(+) hematopoietic progenitor cells induced by the inflammatory mediator leukotriene D4 are mediated by the 7-transmembrane receptor CysLT1. |
| 11956320 | J. Cell. Sci. | 2002 | Paruchuri S et al. | Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells. |
| 20083671 | J. Immunol. | 2010 | Woszczek G et al. | Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists. |
| 14718577 | J. Pharmacol. Exp. Ther. | 2004 | Dupré DJ et al. | Inverse agonist activity of selected ligands of the cysteinyl-leukotriene receptor 1. |
| 25231108 | Am. J. Physiol., Cell Physiol. | 2014 | Arthur S and Sundaram U | Protein kinase C-mediated phosphorylation of RKIP regulates inhibition of Na-alanine cotransport by leukotriene D(4) in intestinal epithelial cells. |