Coenzyme q10 is a lipid of Prenol Lipids (PR) class. Coenzyme q10 is associated with abnormalities such as Nephrotic Syndrome, Diabetes, COENZYME Q10 DEFICIENCY, Deafness and Hypertensive disease. The involved functions are known as Mutation, Process, Oxidation, Electron Transport and Oxidants. Coenzyme q10 often locates in Mitochondria, soluble, Plasma membrane, Body tissue and Inner mitochondrial membrane. The associated genes with Coenzyme Q10 are MT-CYB gene, ATP5B gene, cytochrome c'', STN gene and NPC1 gene. The related lipids are Total cholesterol and Lipid Peroxides. The related experimental models are Mouse Model.
PMID | Journal | Published Date | Author | Title |
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9012647 | Arterioscler. Thromb. Vasc. Biol. | 1997 | de Rijke YB et al. | The redox status of coenzyme Q10 in total LDL as an indicator of in vivo oxidative modification. Studies on subjects with familial combined hyperlipidemia. |
11502580 | Am. J. Physiol., Cell Physiol. | 2001 | Palmeira CM et al. | Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: role of coenzyme Q. |
20668119 | Cancer Epidemiol. Biomarkers Prev. | 2010 | Chai W et al. | Plasma coenzyme Q10 levels and postmenopausal breast cancer risk: the multiethnic cohort study. |
17412732 | Brain | 2007 | Gempel K et al. | The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. |
16905642 | Am. J. Epidemiol. | 2006 | de Lau LM et al. | Serum cholesterol levels and the risk of Parkinson's disease. |
22653988 | J. Appl. Physiol. | 2012 | Muraki A et al. | Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance. |
23018185 | Biol. Reprod. | 2012 | Gendelman M and Roth Z | Incorporation of coenzyme Q10 into bovine oocytes improves mitochondrial features and alleviates the effects of summer thermal stress on developmental competence. |
23727839 | Hum. Mol. Genet. | 2013 | Cornelius N et al. | Secondary coenzyme Q10 deficiency and oxidative stress in cultured fibroblasts from patients with riboflavin responsive multiple Acyl-CoA dehydrogenation deficiency. |
27406740 | Am. J. Physiol. Endocrinol. Metab. | 2016 | Sheeran FL and Pepe S | Posttranslational modifications and dysfunction of mitochondrial enzymes in human heart failure. |
26410779 | Brain Res. | 2015 | Kaisar MA et al. | Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial? |
25625583 | Redox Biol | 2015 | Gueven N et al. | Border between natural product and drug: comparison of the related benzoquinones idebenone and coenzyme Q10. |
25034304 | Mitochondrion | 2014 | Ma D et al. | Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10. |