N,N-dimethylsphingosine

N,N-dimethylsphingosine is a lipid of Sphingolipids (SP) class. N,n-dimethylsphingosine is associated with abnormalities such as Exanthema and Increased drug resistance. The involved functions are known as Vmax, Metabolic Inhibition, Anabolism, Binding (Molecular Function) and Cytokinesis. N,n-dimethylsphingosine often locates in yolk, Membrane, CNS - Brain (MMHCC), soluble and Tissue membrane. The associated genes with N,N-dimethylsphingosine are FPR1 gene, ANP32A gene, HPGDS gene, Nuclear phosphoprotein and PTGS2 gene. The related lipids are Sphingolipids, Phosphatidic Acid, Lysophosphatidylcholines, stearylamine and dihydroceramide. The related experimental models are Mouse Model and Knock-out.

References related to locations published in Others


PMIDJournalPublished DateAuthorTitle
21900594Sci Transl Med2011Yung YC et al.Lysophosphatidic acid signaling may initiate fetal hydrocephalus.
10969794Cancer Res.2000Nava VE et al.Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells.
15643073Eukaryotic Cell2005Min J et al.Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.
16831409Cardiovasc. Res.2006Jin ZQ and Karliner JSLow dose N, N-dimethylsphingosine is cardioprotective and activates cytosolic sphingosine kinase by a PKCepsilon dependent mechanism.