lanosterol

lanosterol is a lipid of Sterol Lipids (ST) class. Lanosterol is associated with abnormalities such as Infection, Atherosclerosis, Myocardial Infarction, Chagas Disease and Fatty Liver. The involved functions are known as Signal, Cytokinesis, physiological aspects, Stereochemistry and ergosterol biosynthetic process. Lanosterol often locates in Body tissue, Membrane, Plasma membrane, Tissue membrane and Cytoskeletal Filaments. The associated genes with lanosterol are Retinoic Acid Response Element, P4HTM gene, CYP51A1 gene, HM13 gene and SC4MOL gene. The related lipids are pneumocysterol, Sterols, lanosteryl acetate, ebericol and cycloartenol. The related experimental models are Knock-out.

References related to locations published in Others


PMIDJournalPublished DateAuthorTitle
22577133J. Biol. Chem.2012Iyoda T et al.Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells.
8621604J. Biol. Chem.1996Shi J et al.Identification and characterization of an S-adenosyl-L-methionine: delta 24-sterol-C-methyltransferase cDNA from soybean.
14757852J. Pharmacol. Exp. Ther.2004Woo KC et al.Phytoestrogen cimicifugoside-mediated inhibition of catecholamine secretion by blocking nicotinic acetylcholine receptor in bovine adrenal chromaffin cells.
21175744FEMS Microbiol. Lett.2011Rosa Ide A et al.Ultrastructural alterations induced by Δ(24(25))-sterol methyltransferase inhibitors on Trichomonas vaginalis.
16272484J. Clin. Microbiol.2005Shimokawa O et al.Relationship between MIC and minimum sterol 14{alpha}-demethylation-inhibitory concentration as a factor in evaluating activities of azoles against various fungal species.
22453923J. Biol. Chem.2012D'Agostino J et al.Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.
20421456Plant Physiol.2010Carland F et al.The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products.
18364712Mol. Syst. Biol.2008Andersen MR et al.Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger.
22147702J. Biol. Chem.2012Shichiri M et al.A novel role for α-tocopherol transfer protein (α-TTP) in protecting against chloroquine toxicity.
21304167MBio2011D'Souza CA et al.Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.
20531405Mol. Syst. Biol.2010Owens CM et al.Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.
20443782Clin. Sci.2010Jarvie E et al.Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring.
19897737Eukaryotic Cell2010Joffrion TM et al.Functional characterization and localization of Pneumocystis carinii lanosterol synthase.
17885082Plant Physiol.2007Chen Q et al.Biosynthesis of phytosterol esters: identification of a sterol o-acyltransferase in Arabidopsis.
16989930Toxicology2006Trösken ER et al.Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.