22-Hydroxycholesterol

22-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 22-hydroxycholesterol is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, Congestive heart failure, Atherosclerosis and Hypercholesterolemia. The involved functions are known as physiological aspects, Regulation, Anabolism, Metabolic Inhibition and Adjudication. 22-hydroxycholesterol often locates in Body tissue, Blood, Mitochondria, Membrane and Tissue membrane. The associated genes with 22-Hydroxycholesterol are Candidate Disease Gene, ABCA1 gene, CLTC gene, SLC22A1 gene and SLC10A1 gene. The related lipids are Hydroxycholesterols, Lipopolysaccharides, 22-hydroxycholesterol, Fatty Acids and (22R)-22-hydroxycholesterol.

References related to locations published in Others

PMID	Journal	Published Date	Author	Title
22169006	Am. J. Physiol. Renal Physiol.	2012	Kittayaruksakul S et al.	Liver X receptor activation downregulates organic anion transporter 1 (OAT1) in the renal proximal tubule.
23110859	Circulation	2012	Valbuena-Diez AC et al.	Oxysterol-induced soluble endoglin release and its involvement in hypertension.
20227267	Prostaglandins Leukot. Essent. Fatty Acids	2010 Apr-Jun	Vallim T and Salter AM	Regulation of hepatic gene expression by saturated fatty acids.
17693624	J. Lipid Res.	2007	Buono C et al.	Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL.
27206966	Biochim. Biophys. Acta	2016	Kim H et al.	22(R)-hydroxycholesterol induces HuR-dependent MAP kinase phosphatase-1 expression via mGluR5-mediated Ca(2+)/PKCα signaling.
26635040	Haematologica	2016	Ceroi A et al.	The anti-inflammatory effects of platelet-derived microparticles in human plasmacytoid dendritic cells involve liver X receptor activation.