20-hydroxyecdysone

20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.

References related to locations published in Others

PMID	Journal	Published Date	Author	Title
9535959	J. Neurophysiol.	1998	Cooper RL and Ruffner ME	Depression of synaptic efficacy at intermolt in crayfish neuromuscular junctions by 20-hydroxyecdysone, a molting hormone.
9786994	J. Neurosci.	1998	Kraft R et al.	The steroid hormone 20-hydroxyecdysone enhances neurite growth of Drosophila mushroom body neurons isolated during metamorphosis.
10373539	Mol. Cell. Biol.	1999	Lan Q et al.	Activation of a delayed-early gene encoding MHR3 by the ecdysone receptor heterodimer EcR-B1-USP-1 but not by EcR-B1-USP-2.
10036278	J. Neurophysiol.	1999	Ruffner ME et al.	Depression of synaptic efficacy in high- and low-output Drosophila neuromuscular junctions by the molting hormone (20-HE).
12522263	Proc. Natl. Acad. Sci. U.S.A.	2003	Zhu J et al.	Cyclicity of mosquito vitellogenic ecdysteroid-mediated signaling is modulated by alternative dimerization of the RXR homologue Ultraspiracle.
21673327	Toxicol. Sci.	2011	Wang YH et al.	Tributyltin synergizes with 20-hydroxyecdysone to produce endocrine toxicity.
19060216	Proc. Natl. Acad. Sci. U.S.A.	2008	Pondeville E et al.	Anopheles gambiae males produce and transfer the vitellogenic steroid hormone 20-hydroxyecdysone to females during mating.
20430856	J Mol Cell Biol	2010	Wang S et al.	20-hydroxyecdysone reduces insect food consumption resulting in fat body lipolysis during molting and pupation.
16324822	Genomics	2006	Wang Y et al.	An expansion of the dual clip-domain serine proteinase family in Manduca sexta: gene organization, expression, and evolution of prophenoloxidase-activating proteinase-2, hemolymph proteinase 12, and other related proteinases.
11333238	Genetics	2001	Venkatesh K et al.	Interactions between the inositol 1,4,5-trisphosphate and cyclic AMP signaling pathways regulate larval molting in Drosophila.