Tetradecanoic acid

Tetradecanoic acid is a lipid of Fatty Acyls (FA) class. Tetradecanoic acid is associated with abnormalities such as Chronic lung disease, Infection, Spastic syndrome, Diabetes and Cardiovascular Diseases. The involved functions are known as Fatty acid biosynthetic process, Anabolism, lung alveolus development, 5-(carboxyamino)imidazole ribonucleotide mutase activity and Homeostasis. Tetradecanoic acid often locates in Structure of parenchyma of lung, Blood, Head, Membrane and Cytoplasmic matrix. The associated genes with Tetradecanoic acid are SLC33A1 gene, SFTPA1 gene, P4HTM gene, Polypeptides and GPR132 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, palmitoleic acid, Phosphatidylglycerols and Butanols.

References related to locations published in Others


PMIDJournalPublished DateAuthorTitle
9427743EMBO J.1998Fincham VJ and Frame MCThe catalytic activity of Src is dispensable for translocation to focal adhesions but controls the turnover of these structures during cell motility.
9436987Mol. Biol. Cell1998Morales J et al.Plasma membrane localization of G alpha z requires two signals.
9103475J. Pharmacol. Exp. Ther.1997Naze S et al.Activation of phospholipase D by endothelin-1 in rat myometrium. Role of calcium and protein kinase C.
11493554Development2001Kohtz JD et al.N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons.
11891256Plant Physiol.2002Lu SX and Hrabak EMAn Arabidopsis calcium-dependent protein kinase is associated with the endoplasmic reticulum.
12118067J. Cell. Sci.2002Navarro-Lérida I et al.Distance-dependent cellular palmitoylation of de-novo-designed sequences and their translocation to plasma membrane subdomains.
12829627Diabetes2003Mittendorfer B et al.What does the measurement of whole-body fatty acid rate of appearance in plasma by using a fatty acid tracer really mean?
12588983Mol. Cell. Biol.2003Razandi M et al.Identification of a structural determinant necessary for the localization and function of estrogen receptor alpha at the plasma membrane.
12455958Eukaryotic Cell2002Shaw BD et al.Aspergillus nidulans swoF encodes an N-myristoyl transferase.
10564270Mol. Biol. Cell1999McCabe JB and Berthiaume LGFunctional roles for fatty acylated amino-terminal domains in subcellular localization.
11099414Science2000Zha J et al.Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis.
10974060J. Lipid Res.2000Bodennec J et al.A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges.
14576428Science2003Hanczyc MM et al.Experimental models of primitive cellular compartments: encapsulation, growth, and division.
15302818Eukaryotic Cell2004Paul KS et al.Multiple triclosan targets in Trypanosoma brucei.
21636561J. Appl. Physiol.2011Bernhard W et al.Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acid supply.
20811010Am. J. Physiol. Regul. Integr. Comp. Physiol.2010Pynn CJ et al.Myristate is selectively incorporated into surfactant and decreases dipalmitoylphosphatidylcholine without functional impairment.
18835981Mol. Pharmacol.2009Fujita A et al.Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain.
20584982Mol. Cell. Biol.2010Patwardhan P and Resh MDMyristoylation and membrane binding regulate c-Src stability and kinase activity.
15342784Mol. Biol. Cell2004Tull D et al.SMP-1, a member of a new family of small myristoylated proteins in kinetoplastid parasites, is targeted to the flagellum membrane in Leishmania.
17977947Am. J. Physiol., Cell Physiol.2008White J et al.Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin.
17586653Plant Cell2007Yin XJ et al.Ubiquitin lysine 63 chain forming ligases regulate apical dominance in Arabidopsis.
17616681Cancer Res.2007Adam RM et al.Cholesterol sensitivity of endogenous and myristoylated Akt.
16569659J. Cell. Sci.2006Navarro-Lérida I et al.N-terminal palmitoylation within the appropriate amino acid environment conveys on NOS2 the ability to progress along the intracellular sorting pathways.
21965604FASEB J.2012Martin DD et al.Tandem reporter assay for myristoylated proteins post-translationally (TRAMPP) identifies novel substrates for post-translational myristoylation: PKCε, a case study.
24390393Plant Physiol.2014Yu G and Pichersky EHeterologous expression of methylketone synthase1 and methylketone synthase2 leads to production of methylketones and myristic acid in transgenic plants.
20971967Diabetes2011Elsner M et al.Peroxisome-generated hydrogen peroxide as important mediator of lipotoxicity in insulin-producing cells.
19357638Mol. Syst. Biol.2009Atherton HJ et al.Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse.
22345606Genetics2012Henry SA et al.Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae.
22085962Genes Dev.2011Wright KJ et al.An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium.
19934003Diabetes2010Yeop Han C et al.Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation.
18068687Biochem. Pharmacol.2008Isenberg JS et al.Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells.
17169445Mol. Biochem. Parasitol.2007Mills E et al.Kinetoplastid PPEF phosphatases: dual acylated proteins expressed in the endomembrane system of Leishmania.
15657075J. Cell. Sci.2005Stegmayer C et al.Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant.
11994481J. Immunol.2002D'Hauteville H et al.Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium.
11284718Biochem. J.2001Guzzi F et al.Thioacylation is required for targeting G-protein subunit G(o1alpha) to detergent-insoluble caveolin-containing membrane domains.
11152728J. Neurophysiol.2001Angleson JK and Betz WJIntraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junction.
28137759J. Cell. Sci.2017Demetriadou A et al.Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology.
27237364Cell Host Microbe2016Trindade S et al.Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice.
26278174Structure2015Zhang P et al.An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes.
24680960Int J Pharm2014Pettit MW et al.Construction and physiochemical characterisation of a multi-composite, potential oral vaccine delivery system (VDS).