Cholic acid
Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.
References related to locations published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 10037814 | Nucleic Acids Res. | 1999 | Wu L and Curran JF | An allosteric synthetic DNA. |
| 11328782 | J. Antimicrob. Chemother. | 2001 | Schmidt EJ et al. | Activities of cholic acid-derived antimicrobial agents against multidrug-resistant bacteria. |
| 10756198 | Nucleic Acids Res. | 2000 | Kato T et al. | Interaction of three-way DNA junctions with steroids. |
| 21518881 | Proc. Natl. Acad. Sci. U.S.A. | 2011 | Siggs OM et al. | X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C. |
| 15574918 | Appl. Environ. Microbiol. | 2004 | Elkins CA and Mullis LB | Bile-mediated aminoglycoside sensitivity in Lactobacillus species likely results from increased membrane permeability attributable to cholic acid. |
| 18583509 | Drug Metab. Dispos. | 2008 | Deo AK and Bandiera SM | Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid. |
| 20884752 | J. Pharmacol. Exp. Ther. | 2011 | Miyata M et al. | Enterobacteria modulate intestinal bile acid transport and homeostasis through apical sodium-dependent bile acid transporter (SLC10A2) expression. |
| 27151938 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2016 | Sun L et al. | Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. |
| 14050761 | Cancer Res. | 1963 | SONGSTER CL et al. | METABOLISM OF BILE COMPONENTS DURING HEPATOCARCINOGENESIS. I. CONJUGATION OF CHOLIC ACID IN VITRO IN EXPERIMENTAL LIVER CARCINOGENESIS. |