Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model.
PMID | Journal | Published Date | Author | Title |
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27806275 | Biophys. J. | 2016 | Fricke N and Dimova R | GM1 Softens POPC Membranes and Induces the Formation of Micron-Sized Domains. |
27806280 | Biophys. J. | 2016 | Patel DS et al. | Influence of Ganglioside GM1 Concentration on Lipid Clustering and Membrane Properties and Curvature. |
27006465 | MBio | 2016 | Luo Y et al. | Interaction between Simian Virus 40 Major Capsid Protein VP1 and Cell Surface Ganglioside GM1 Triggers Vacuole Formation. |
26130766 | J. Lipid Res. | 2015 | Huang FT et al. | A facile method for controlling the reaction equilibrium of sphingolipid ceramide N-deacylase for lyso-glycosphingolipid production. |
26099170 | J. Neurol. Sci. | 2015 | Schneider JS et al. | GM1 ganglioside in Parkinson's disease: Pilot study of effects on dopamine transporter binding. |
24685176 | Neuron | 2014 | Hong S et al. | Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes. |
24531750 | Cancer Res. | 2014 | Romero I et al. | T lymphocytes restrain spontaneous metastases in permanent dormancy. |
24525187 | Dev. Cell | 2014 | Cohen R et al. | Lipid modulation of calcium flux through CaV2.3 regulates acrosome exocytosis and fertilization. |
24370893 | J Control Release | 2014 | te Welscher YM et al. | Unsaturated glycoceramides as molecular carriers for mucosal drug delivery of GLP-1. |
23111873 | MBio | 2012 | Jobling MG et al. | A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway. |
22975326 | Dev. Cell | 2012 | Chinnapen DJ et al. | Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1. |
22824274 | Biophys. J. | 2012 | Štefl M et al. | Dynamics and size of cross-linking-induced lipid nanodomains in model membranes. |
22529395 | Proc. Natl. Acad. Sci. U.S.A. | 2012 | Puryear WB et al. | HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells. |
22331905 | Proc. Natl. Acad. Sci. U.S.A. | 2012 | Di Pardo A et al. | Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice. |
22118676 | Chem. Biol. | 2011 | Sanghera N et al. | Deciphering the molecular details for the binding of the prion protein to main ganglioside GM1 of neuronal membranes. |
21788572 | Diabetes | 2011 | Wu G et al. | Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression. |
21723896 | Neurochem. Int. | 2011 | Kreutz F et al. | Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action. |
20206128 | Biochem. Biophys. Res. Commun. | 2010 | Chebukati JN et al. | Bis(monoacylglycero)phosphate and ganglioside GM1 spontaneously form small homogeneous vesicles at specific concentrations. |
20148761 | Biochem. J. | 2010 | Cole AA et al. | Co-segregation of AMPA receptors with G(M1) ganglioside in synaptosomal membrane subfractions. |
19917257 | Mol. Cell | 2009 | Sano R et al. | GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis. |
19625649 | J. Immunol. | 2009 | Bodhankar S et al. | NK cells interfere with the generation of resistance against mycoplasma respiratory infection following nasal-pulmonary immunization. |
19541636 | Proc. Natl. Acad. Sci. U.S.A. | 2009 | Wu G et al. | Sodium-calcium exchanger complexed with GM1 ganglioside in nuclear membrane transfers calcium from nucleoplasm to endoplasmic reticulum. |
19299701 | J. Immunol. | 2009 | Wang J et al. | Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis. |
19118221 | J. Cell. Sci. | 2009 | Ichikawa N et al. | Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth. |
18628305 | J. Cell. Sci. | 2008 | Hofman EG et al. | EGF induces coalescence of different lipid rafts. |
18603643 | J. Lipid Res. | 2008 | Chen Y et al. | Fluorescence-topographic NSOM directly visualizes peak-valley polarities of GM1/GM3 rafts in cell membrane fluctuations. |
18192361 | Biophys. J. | 2008 | Frey SL et al. | Condensing and fluidizing effects of ganglioside GM1 on phospholipid films. |
18032586 | Mol. Biol. Cell | 2008 | Galvan C et al. | Anomalous surface distribution of glycosyl phosphatidyl inositol-anchored proteins in neurons lacking acid sphingomyelinase. |
17855525 | J. Virol. | 2007 | Campanero-Rhodes MA et al. | N-glycolyl GM1 ganglioside as a receptor for simian virus 40. |
17428969 | J. Neurosci. | 2007 | Susuki K et al. | Anti-GM1 antibodies cause complement-mediated disruption of sodium channel clusters in peripheral motor nerve fibers. |
17312105 | J. Immunol. | 2007 | Moore ML et al. | Cutting Edge: Oseltamivir decreases T cell GM1 expression and inhibits clearance of respiratory syncytial virus: potential role of endogenous sialidase in antiviral immunity. |
16818778 | J. Immunol. | 2006 | Zoeteweij JP et al. | GM1 binding-deficient exotoxin is a potent noninflammatory broad spectrum intradermal immunoadjuvant. |
16393952 | J. Immunol. | 2006 | Legembre P et al. | Modulation of Fas-mediated apoptosis by lipid rafts in T lymphocytes. |
16306414 | J. Neurosci. | 2005 | Wu G et al. | Enhanced susceptibility to kainate-induced seizures, neuronal apoptosis, and death in mice lacking gangliotetraose gangliosides: protection with LIGA 20, a membrane-permeant analog of GM1. |
16237053 | J. Immunol. | 2005 | Rouquette-Jazdanian AK et al. | Cholera toxin B-subunit prevents activation and proliferation of human CD4+ T cells by activation of a neutral sphingomyelinase in lipid rafts. |
16140785 | J. Virol. | 2005 | Jolly C and Sattentau QJ | Human immunodeficiency virus type 1 virological synapse formation in T cells requires lipid raft integrity. |
15972641 | J. Immunol. | 2005 | Kim JH et al. | Independent trafficking of Ig-alpha/Ig-beta and mu-heavy chain is facilitated by dissociation of the B cell antigen receptor complex. |
15879469 | Biophys. J. | 2005 | Burns AR et al. | Local mobility in lipid domains of supported bilayers characterized by atomic force microscopy and fluorescence correlation spectroscopy. |
15851688 | Proc. Natl. Acad. Sci. U.S.A. | 2005 | Hammond AT et al. | Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes. |
15772422 | J. Lipid Res. | 2005 | Nakagawa T et al. | C18:3-GM1a induces apoptosis in Neuro2a cells: enzymatic remodeling of fatty acyl chains of glycosphingolipids. |
15643001 | Clin. Diagn. Lab. Immunol. | 2005 | Shimizu T et al. | Induction of thymus-derived gammadelta T Cells by Escherichia coli enterotoxin b subunit in peritoneal cavities of mice. |
15447995 | Clin. Cancer Res. | 2004 | Krug LM et al. | Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin. |
15350219 | Mol. Cell | 2004 | Tessitore A et al. | GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis. |
15277677 | Proc. Natl. Acad. Sci. U.S.A. | 2004 | Yuki N et al. | Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome. |
15034144 | Mol. Biol. Cell | 2004 | Wilson BS et al. | Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes. |
15004155 | J. Immunol. | 2004 | Chen CJ and Shively JE | The cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1 inhibits IL-2 production and proliferation in human T cells by association with Src homology protein-1 and down-regulates IL-2 receptor. |
14996913 | J. Cell. Sci. | 2004 | Pang H et al. | Ganglioside GM1 levels are a determinant of the extent of caveolae/raft-dependent endocytosis of cholera toxin to the Golgi apparatus. |
14967068 | Biochem. J. | 2004 | Iwamori M and Domino SE | Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes. |
14871967 | Clin. Cancer Res. | 2004 | Krug LM et al. | Vaccination of small cell lung cancer patients with polysialic acid or N-propionylated polysialic acid conjugated to keyhole limpet hemocyanin. |
12960303 | J. Immunol. | 2003 | Hare KJ et al. | Modeling TCR signaling complex formation in positive selection. |
12881314 | Blood | 2003 | de Gassart A et al. | Lipid raft-associated protein sorting in exosomes. |
12816985 | J. Immunol. | 2003 | Jordan S and Rodgers W | T cell glycolipid-enriched membrane domains are constitutively assembled as membrane patches that translocate to immune synapses. |
12642099 | Virology | 2003 | Jeffree CE et al. | Distribution of the attachment (G) glycoprotein and GM1 within the envelope of mature respiratory syncytial virus filaments revealed using field emission scanning electron microscopy. |
12634387 | J. Virol. | 2003 | Ong KW et al. | The B subunit of Escherichia coli heat-labile enterotoxin enhances CD8+ cytotoxic-T-lymphocyte killing of Epstein-Barr virus-infected cell lines. |
12514198 | J. Neurosci. | 2003 | Matsuoka Y et al. | Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid. |
12391328 | Proc. Natl. Acad. Sci. U.S.A. | 2002 | Wong AP and Groves JT | Molecular topography imaging by intermembrane fluorescence resonance energy transfer. |
12384415 | Blood | 2002 | Ito M et al. | NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. |
12196287 | Immunity | 2002 | Dupré L et al. | Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation. |
11917140 | Proc. Natl. Acad. Sci. U.S.A. | 2002 | Rusnati M et al. | Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2. |
11884440 | J. Immunol. | 2002 | Mitchell JS et al. | Lipid microdomain clustering induces a redistribution of antigen recognition and adhesion molecules on human T lymphocytes. |
11877482 | J. Exp. Med. | 2002 | Bavari S et al. | Lipid raft microdomains: a gateway for compartmentalized trafficking of Ebola and Marburg viruses. |
11865037 | J. Cell. Sci. | 2002 | Majoul I et al. | Differential expression of receptors for Shiga and Cholera toxin is regulated by the cell cycle. |
11675488 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Sugimoto Y et al. | Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells. |
11606627 | J. Neurosci. | 2001 | Rodriguez JA et al. | Plasma membrane ganglioside sialidase regulates axonal growth and regeneration in hippocampal neurons in culture. |
11598189 | Mol. Biol. Cell | 2001 | Stuermer CA et al. | Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2. |
11531335 | J. Mol. Biol. | 2001 | Daniell H et al. | Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts. |
11520799 | Blood | 2001 | Marmor MD and Julius M | Role for lipid rafts in regulating interleukin-2 receptor signaling. |
11504934 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Pierini LM and Maxfield FR | Flotillas of lipid rafts fore and aft. |
11481474 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | McNamara N et al. | ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor. |
11447291 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Aman AT et al. | A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity. |
11283076 | J. Clin. Microbiol. | 2001 | Prendergast MM et al. | Development of an immunoassay for rapid detection of ganglioside GM(1) mimicry in Campylobacter jejuni strains. |
11172001 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Giraudo CG et al. | Physical and functional association of glycolipid N-acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus. |
11171945 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | van Meer G | What sugar next? Dimerization of sphingolipid glycosyltransferases. |
11113142 | ||||
11045998 | J. Immunol. | 2000 | van Ginkel FW et al. | Cutting edge: the mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. |
10981968 | Immunity | 2000 | Shamshiev A et al. | The alphabeta T cell response to self-glycolipids shows a novel mechanism of CD1b loading and a requirement for complex oligosaccharides. |
10871308 | J. Pharmacol. Exp. Ther. | 2000 | Galisteo M et al. | Hepatotoxicity of tacrine: occurrence of membrane fluidity alterations without involvement of lipid peroxidation. |
10793141 | Mol. Biol. Cell | 2000 | Kenworthy AK et al. | High-resolution FRET microscopy of cholera toxin B-subunit and GPI-anchored proteins in cell plasma membranes. |
10640746 | J. Immunol. | 2000 | Dillon SR et al. | Annexin V binds to viable B cells and colocalizes with a marker of lipid rafts upon B cell receptor activation. |
11124999 | J. Neurosci. | 2000 | Jasmin L et al. | Schwann cells are removed from the spinal cord after effecting recovery from paraplegia. |
10406985 | J. Neurol. Neurosurg. Psychiatry | 1999 | Kuwabara S et al. | Hyperreflexia in Guillain-Barré syndrome: relation with acute motor axonal neuropathy and anti-GM1 antibody. |
9971824 | J. Virol. | 1999 | Fujioka N et al. | Interleukin-18 protects mice against acute herpes simplex virus type 1 infection. |
9650959 | J. Clin. Microbiol. | 1998 | Sack DA et al. | Microtiter assay for detecting Campylobacter spp. and Helicobacter pylori with surface gangliosides which bind cholera toxin. |
9585412 | J. Cell Biol. | 1998 | Harder T et al. | Lipid domain structure of the plasma membrane revealed by patching of membrane components. |
9585411 | J. Cell Biol. | 1998 | Wolf AA et al. | Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia. |
9384564 | Structure | 1997 | Merritt EA et al. | Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin. |
9144230 | Proc. Natl. Acad. Sci. U.S.A. | 1997 | Williams NA et al. | Prevention of autoimmune disease due to lymphocyte modulation by the B-subunit of Escherichia coli heat-labile enterotoxin. |
9169834 | Development | 1997 | Joliot A et al. | Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties. |
9064322 | J. Exp. Med. | 1996 | Frey A et al. | Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. |
8623106 | Stroke | 1996 | Grieco G et al. | Evaluating neuroprotective agents for clinical anti-ischemic benefit using neurological and neuropsychological changes after cardiac surgery under cardiopulmonary bypass. Methodological strategies and results of a double-blind, placebo-controlled trial of GM1 ganglioside. |
7751942 | J. Neurosci. | 1995 | Wu G et al. | Induced and spontaneous neuritogenesis are associated with enhanced expression of ganglioside GM1 in the nuclear membrane. |
7908958 | J. Neurosci. | 1994 | Mao J et al. | Thermal hyperalgesia in association with the development of morphine tolerance in rats: roles of excitatory amino acid receptors and protein kinase C. |
8410039 | J. Neurol. Neurosurg. Psychiatry | 1993 | Adams D et al. | Motor conduction block and high titres of anti-GM1 ganglioside antibodies: pathological evidence of a motor neuropathy in a patient with lower motor neuron syndrome. |
8478681 | J. Neurosci. | 1993 | Ferrari G et al. | Gangliosides rescue neuronal cells from death after trophic factor deprivation. |
3257715 | Cancer Res. | 1988 | Kawase I et al. | Combined therapy of mice bearing a lymphokine-activated killer-resistant tumor with recombinant interleukin 2 and an antitumor monoclonal antibody capable of inducing antibody-dependent cellular cytotoxicity. |
457774 | J. Cell Biol. | 1979 | Joseph KC et al. | Endocytosis of cholera toxin in GERL-like structures of murine neuroblastoma cells pretreated with GM1 ganglioside. Cholera toxin internalization into Neuroblastoma GERL. |
11525808 | J. Neuroimmunol. | 2001 | Ortiz N et al. | IgM monoclonal antibody against terminal moiety of GM2, GalNAc-GD1a and GalNAc-GM1b from a pure motor chronic demyelinating polyneuropathy patient: effects on neurotransmitter release. |
18241673 | Clin. Biochem. | 2008 | Gu J et al. | Simultaneous quantification of GM1 and GM2 gangliosides by isotope dilution tandem mass spectrometry. |
11578853 | Brain Dev. | 2001 | Taniguchi M et al. | Sites and temporal changes of gangliosides GM1/GM2 storage in the Niemann-Pick disease type C mouse brain. |
10497993 | Am. J. Trop. Med. Hyg. | 1999 | Gori AH et al. | Mediation of attachment of Burkholderia pseudomallei to human pharyngeal epithelial cells by the asialoganglioside GM1-GM2 receptor complex. |
15652411 | J. Neuroimmunol. | 2005 | Hirakawa M et al. | Effects of phospholipids on antiganglioside antibody reactivity in GBS. |
19560125 | Carbohydr. Res. | 2009 | Komori T et al. | Study on systematizing the synthesis of the a-series ganglioside glycans GT1a, GD1a, and GM1 using the newly developed N-Troc-protected GM3 and GalN intermediates. |
18077059 | Neurobiol. Aging | 2009 | Zhang H et al. | Ganglioside GM1 binding the N-terminus of amyloid precursor protein. |
28499578 | Biophys. Chem. | 2017 | Rondelli V et al. | Building a biomimetic membrane for neutron reflectivity investigation: Complexity, asymmetry and contrast. |
28410623 | Biophys. J. | 2017 | Cebecauer M et al. | Impact of GM1 on Membrane-Mediated Aggregation/Oligomerization of β-Amyloid: Unifying View. |
27815022 | Neuroscience | 2017 | Kasahara R et al. | The σ1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes. |
26948382 | J Control Release | 2016 | Haroon MM et al. | A designed recombinant fusion protein for targeted delivery of siRNA to the mouse brain. |
26259785 | Biophys. Chem. | 2016 | Nicastro MC et al. | Amyloid β-peptide insertion in liposomes containing GM1-cholesterol domains. |
26024958 | Trends Biochem. Sci. | 2015 | Ledeen RW and Wu G | The multi-tasked life of GM1 ganglioside, a true factotum of nature. |
26021803 | Mol. Immunol. | 2015 | Phongsisay V et al. | Evidence for TLR4 and FcRγ-CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors. |
25600806 | Biochem. Biophys. Res. Commun. | 2015 | Yamamoto N et al. | Midazolam inhibits the formation of amyloid fibrils and GM1 ganglioside-rich microdomains in presynaptic membranes through the gamma-aminobutyric acid A receptor. |
25448159 | Exp. Neurol. | 2015 | Hadaczek P et al. | GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model. |
25283719 | J. Neuroimmunol. | 2014 | Notturno F et al. | Autoantibodies to neurofascin-186 and gliomedin in multifocal motor neuropathy. |
25157033 | J. Neurol. Neurosurg. Psychiatry | 2015 | Cats EA et al. | Clonality of anti-GM1 IgM antibodies in multifocal motor neuropathy and the Guillain-Barré syndrome. |
24524938 | Colloids Surf B Biointerfaces | 2014 | Schulte W et al. | A Langmuir monolayer study of the action of phospholipase A2 on model phospholipid and mixed phospholipid-GM1 ganglioside membranes. |
24229616 | Lancet Neurol | 2013 | Kuwabara S and Yuki N | Axonal Guillain-Barré syndrome: concepts and controversies. |
22634013 | Biochem. Biophys. Res. Commun. | 2012 | Mrówczyńska L et al. | Spontaneous curvature of ganglioside GM1--effect of cross-linking. |
22542816 | Vaccine | 2012 | Miyata T et al. | Physicochemically stable cholera toxin B subunit pentamer created by peripheral molecular constraints imposed by de novo-introduced intersubunit disulfide crosslinks. |
22450166 | Dev. Comp. Immunol. | 2012 | Garcia-Garcia E et al. | Evidence for the presence of functional lipid rafts in immune cells of ectothermic organisms. |
22071505 | FASEB J. | 2012 | Bucciantini M et al. | Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1. |
21820419 | Biochem. Pharmacol. | 2011 | Rufini S et al. | The sterile alpha-motif (SAM) domain of p63 binds in vitro monoasialoganglioside (GM1) micelles. |
21071752 | J. Neurol. Neurosurg. Psychiatry | 2011 | Kuwabara S et al. | Neuromuscular transmission is not impaired in axonal Guillain--Barré syndrome. |
20858460 | Biochem. Biophys. Res. Commun. | 2010 | Mrówczyńska L et al. | Echinophilic proteins stomatin, sorcin, and synexin locate outside gangliosideM1 (GM1) patches in the erythrocyte membrane. |
20825794 | Am J Emerg Med | 2011 | Hu H et al. | Factors affecting the prognosis of patients with delayed encephalopathy after acute carbon monoxide poisoning. |
20659560 | Mol. Cell. Neurosci. | 2010 | Ueda A et al. | Anti-GM1 antibodies affect the integrity of lipid rafts. |
20171893 | J Clin Neurosci | 2010 | Huang F et al. | GM1 and nerve growth factor modulate mitochondrial membrane potential and neurofilament light mRNA expression in cultured dorsal root ganglion and spinal cord neurons during excitotoxic glutamate exposure. |
20114052 | J. Mol. Biol. | 2010 | Di Pasquale E et al. | Altered ion channel formation by the Parkinson's-disease-linked E46K mutant of alpha-synuclein is corrected by GM3 but not by GM1 gangliosides. |
20044989 | Eur. J. Pharmacol. | 2010 | Valdomero A et al. | GM1 ganglioside enhances the rewarding properties of cocaine in rats. |
19428361 | Chem. Phys. Lipids | 2009 | Mikhalyov I et al. | Fluorescent BODIPY-labelled GM1 gangliosides designed for exploring lipid membrane properties and specific membrane-target interactions. |
19015484 | Neurology | 2008 | Kaida K et al. | GM1/GalNAc-GD1a complex: a target for pure motor Guillain-Barre syndrome. |
18835310 | Neurochem. Int. | 2008 | Furian AF et al. | L-NAME prevents GM1 ganglioside-induced vasodilation in the rat brain. |
18329889 | Cytokine | 2008 | Vieira KP et al. | Ganglioside GM1 effects on the expression of nerve growth factor (NGF), Trk-A receptor, proinflammatory cytokines and on autoimmune diabetes onset in non-obese diabetic (NOD) mice. |
17697937 | Free Radic. Biol. Med. | 2007 | Furian AF et al. | GM1 ganglioside induces vasodilation and increases catalase content in the brain. |
17582434 | J. Mol. Biol. | 2007 | Okada T et al. | Formation of toxic fibrils of Alzheimer's amyloid beta-protein-(1-40) by monosialoganglioside GM1, a neuronal membrane component. |
17459336 | Biochem. Biophys. Res. Commun. | 2007 | Katsumata O et al. | Syntaxin6 separates from GM1a-rich membrane microdomain during granule maturation. |
17161468 | J. Neuroimmunol. | 2007 | van Sorge NM et al. | Leukocyte and complement activation by GM1-specific antibodies is associated with acute motor axonal neuropathy in rabbits. |
17156858 | J. Neuroimmunol. | 2007 | van Sorge NM et al. | Ganglioside-specific IgG and IgA recruit leukocyte effector functions in Guillain-Barré syndrome. |
17113161 | J. Neuroimmunol. | 2007 | Kaida K et al. | Anti-ganglioside complex antibodies associated with severe disability in GBS. |
16962073 | Biochem. Pharmacol. | 2006 | Gorria M et al. | Protective effect of monosialoganglioside GM1 against chemically induced apoptosis through targeting of mitochondrial function and iron transport. |
16766047 | J. Neuroimmunol. | 2006 | Alaedini A and Latov N | Transglutaminase-independent binding of gliadin to intestinal brush border membrane and GM1 ganglioside. |
16730958 | Colloids Surf B Biointerfaces | 2006 | Weng KC et al. | Fluid supported lipid bilayers containing monosialoganglioside GM1: a QCM-D and FRAP study. |
16343699 | Vaccine | 2006 | Montaner AD et al. | Ganglioside GM1-binding peptides as adjuvants of antigens inoculated by the intranasal route. |
16213682 | J Ethnopharmacol | 2006 | Chen JC et al. | Anti-diarrheal effect of Galla Chinensis on the Escherichia coli heat-labile enterotoxin and ganglioside interaction. |
16084500 | Brain Res. | 2005 | Mo L et al. | GM1 and ERK signaling in the aged brain. |
16024127 | J. Biotechnol. | 2005 | Gong Z et al. | Oral administration of a cholera toxin B subunit-insulin fusion protein produced in silkworm protects against autoimmune diabetes. |
15748609 | Clin. Chim. Acta | 2005 | Sano R et al. | G(M1)-ganglioside degradation and biosynthesis in human and murine G(M1)-gangliosidosis. |
15194154 | Microb. Pathog. | 2004 | Bhattacharyya S et al. | Effect of W07-toxin on gut physiological response in mice. |
15063003 | Peptides | 2004 | Kurganov B et al. | Aggregation of liposomes induced by the toxic peptides Alzheimer's Abetas, human amylin and prion (106-126): facilitation by membrane-bound GM1 ganglioside. |
15037698 | Neurology | 2004 | Susuki K et al. | Acute motor axonal neuropathy after Mycoplasma infection: Evidence of molecular mimicry. |
14698848 | J. Neuroimmunol. | 2004 | Lee G et al. | Induction of human IgM and IgG anti-GM1 antibodies in transgenic mice in response to lipopolysaccharides from Campylobacter jejuni. |
14672816 | Brain Res. | 2004 | Crain SM and Shen KF | Neuraminidase inhibitor, oseltamivir blocks GM1 ganglioside-regulated excitatory opioid receptor-mediated hyperalgesia, enhances opioid analgesia and attenuates tolerance in mice. |
14630342 | Neurosci. Res. | 2003 | O'Hanlon GM et al. | Ganglioside GM1 binding toxins and human neuropathy-associated IgM antibodies differentially promote neuritogenesis in a PC12 assay. |
14552908 | Exp. Neurol. | 2003 | Goettl VM et al. | GM1 enhances dopaminergic markers in the brain of aged rats. |
12799031 | J. Neuroimmunol. | 2003 | Farbu E et al. | GM1 antibodies in post-polio syndrome and previous paralytic polio. |
12763482 | Clin. Immunol. | 2003 | Wadehra M et al. | The tetraspan protein EMP2 increases surface expression of class I major histocompatibility complex proteins and susceptibility to CTL-mediated cell death. |
12667680 | J. Immunol. Methods | 2003 | Thomas S et al. | Sensitive detection of GM1 lipid rafts and TCR partitioning in the T cell membrane. |
12505717 | J. Immunol. Methods | 2003 | Durowicz S and Olszewski WL | A liver perfusion model for studies of selective adherence and transient halting of portal blood leukocytes in sinusoids. |
12470704 | Neurochem. Int. | 2003 | Barrier L et al. | Sulfatide and GM1 ganglioside modulate the high-affinity dopamine uptake in rat striatal synaptosomes: evidence for the involvement of their ionic charges. |
12117481 | Neuromuscul. Disord. | 2002 | Toscano A et al. | Multifocal motor neuropathy and asymptomatic Hashimoto's thyroiditis: first report of an association. |
11960653 | J. Neuroimmunol. | 2002 | Escande-Beillard N et al. | A sensitive flow cytometry method for anti-GM1 antibodies detection. |
11825769 | Microbes Infect. | 2002 | Nakano Y et al. | Roles of NKT cells in resistance against infection with Toxoplasma gondii and in expression of heat shock protein 65 in the host macrophages. |
11525810 | J. Neuroimmunol. | 2001 | Lopez PH et al. | Variable patterns of anti-GM(1) IgM-antibody populations defined by affinity and fine specificity in patients with motor syndromes: evidence for their random origin. |
11430865 | Brain Res. | 2001 | Goettl VM et al. | Motoric behavior in aged rats treated with GM1. |
11282149 | J. Neuroimmunol. | 2001 | Nobile-Orazio E | Multifocal motor neuropathy. |
10843854 | J. Mol. Biol. | 2000 | Hazes B et al. | Crystal structure of Pseudomonas aeruginosa PAK pilin suggests a main-chain-dominated mode of receptor binding. |
10837887 | Brain Res. Dev. Brain Res. | 2000 | Colella R et al. | GM1 enhances the association of neuron-specific MAP2 with actin in MAP2-transfected 3T3 cells. |
10831769 | J. Neurol. Sci. | 2000 | Odaka M et al. | Antibodies to GM1(NeuGc) in Guillain-Barré syndrome after ganglioside therapy. |
10751258 | Neurology | 2000 | Kanda T et al. | Glycosphingolipid antibodies and blood-nerve barrier in autoimmune demyelinative neuropathy. |
10708690 | Brain Res. | 2000 | Goettl VM et al. | GM1 ganglioside restores abnormal responses to acute thermal and mechanical stimuli in aged rats. |
10708681 | Brain Res. | 2000 | Guelman LR et al. | GM1 ganglioside treatment protects against long-term neurotoxic effects of neonatal X-irradiation on cerebellar cortex cytoarchitecture and motor function. |
10695718 | J. Neuroimmunol. | 1999 | Hughes RA et al. | Pathogenesis of Guillain-Barré syndrome. |
10547418 | Vaccine | 1999 | Lian T et al. | Formulation of HIV-envelope protein with lipid vesicles expressing ganglioside GM1 associated to cholera toxin B enhances mucosal immune responses. |
10487390 | Alcohol | 1999 | Brandão F et al. | GM1 and piracetam do not revert the alcohol-induced depletion of cholinergic fibers in the hippocampal formation of the rat. |
10407137 | Brain Res. Dev. Brain Res. | 1999 | Kozireski-Chuback D et al. | Developmental appearance of nuclear GM1 in neurons of the central and peripheral nervous systems. |
10098329 | Immunol. Today | 1999 | Williams NA et al. | Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic. |
10096424 | Cancer Lett. | 1999 | Bolot G et al. | Occurrence of monosialosyl pentahexaosylceramide GalNAc-GM1 as specific tumor-associated ganglioside of human head and neck squamous cell carcinomas. |
9813248 | Brain Res. | 1998 | Panni MK et al. | Ganglioside GM1 potentiates NGF action on axotomised medial septal cholinergic neurons. |
9786023 | Trends Pharmacol. Sci. | 1998 | Crain SM and Shen KF | Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions. |
9658569 | Carbohydr. Res. | 1998 | Müthing J et al. | Glycosphingolipids of skeletal muscle: I. Subcellular distribution of neutral glycosphingolipids and gangliosides in rabbit skeletal muscle. |
9656423 | Vet. Immunol. Immunopathol. | 1998 | Cox NR et al. | Thymic alterations in feline GM1 gangliosidosis. |
9541741 | Brain Res. Dev. Brain Res. | 1998 | Wang LJ et al. | Ganglioside GM1 alters neuronal morphology by modulating the association of MAP2 with microtubules and actin filaments. |
9408194 | Pharmacol. Biochem. Behav. | 1997 | Schroeder H et al. | The role of striatal glutamatergic system in haloperidol-induced dopamine receptor supersensitivity and effects of monosialoganglioside GM1. |
9367259 | Brain Res. | 1997 | Heidinger V et al. | Peptide growth factors but not ganglioside protect against excitotoxicity in rat retinal neurons in vitro. |
9357448 | J. Neuroimmunol. | 1997 | Jacobs BC et al. | Humoral immune response against Campylobacter jejuni lipopolysaccharides in Guillain-Barré and Miller Fisher syndrome. |
7511641 | J. Immunol. | 1994 | Gouy H et al. | Cell calcium signaling via GM1 cell surface gangliosides in the human Jurkat T cell line. |
1828259 | J. Immunol. | 1991 | De Ruysscher D et al. | A subset of asialo GM1+ cells play a protective role in the occurrence of graft-versus-host disease in mice. |
3018079 | J. Immunol. | 1986 | Godeny EK and Gauntt CJ | Involvement of natural killer cells in coxsackievirus B3-induced murine myocarditis. |
3711664 | J. Immunol. | 1986 | Kawano Y et al. | Synergistic defense system by cooperative natural effectors against metastasis of B16 melanoma cells in H-2-associated control: different behavior of H-2+ and H-2- cells in metastatic processes. |
824730 | Science | 1976 | Read DH et al. | Neuronal-visceral GM1 gangliosidosis in a dog with beta-galactosidase deficiency. |