cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model.
|11257033||Antimicrob. Agents Chemother.||2001||Ramaswamy M et al.||Amphotericin B lipid complex or amphotericin B multiple-dose administration to rabbits with elevated plasma cholesterol levels: pharmacokinetics in plasma and blood, plasma lipoprotein levels, distribution in tissues, and renal toxicities.|
|12668600||Hum. Mol. Genet.||2003||Herman GE||Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes.|
|14764421||Arterioscler. Thromb. Vasc. Biol.||2004||Björkhem I and Meaney S||Brain cholesterol: long secret life behind a barrier.|
|20305089||Mol. Cell Proteomics||2010||Jiang XS et al.||Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency.|
|17575085||Diabetes||2007||Hao M et al.||Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction.|
|18238900||Proc. Natl. Acad. Sci. U.S.A.||2008||Kim HJ et al.||Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.|
|18292185||Am. J. Physiol. Gastrointest. Liver Physiol.||2008||Wooton-Kee CR et al.||Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat.|