cholesterol

cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model.

References related to experimental models published in Others

PMID	Journal	Published Date	Author	Title
11257033	Antimicrob. Agents Chemother.	2001	Ramaswamy M et al.	Amphotericin B lipid complex or amphotericin B multiple-dose administration to rabbits with elevated plasma cholesterol levels: pharmacokinetics in plasma and blood, plasma lipoprotein levels, distribution in tissues, and renal toxicities.
12668600	Hum. Mol. Genet.	2003	Herman GE	Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes.
14764421	Arterioscler. Thromb. Vasc. Biol.	2004	Björkhem I and Meaney S	Brain cholesterol: long secret life behind a barrier.
20305089	Mol. Cell Proteomics	2010	Jiang XS et al.	Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency.
17575085	Diabetes	2007	Hao M et al.	Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction.
18238900	Proc. Natl. Acad. Sci. U.S.A.	2008	Kim HJ et al.	Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia.
18292185	Am. J. Physiol. Gastrointest. Liver Physiol.	2008	Wooton-Kee CR et al.	Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat.