Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

References related to pathways published in Others

PMIDJournalPublished DateAuthorTitle
11042147Genome Res.2000Smit A and Mushegian ABiosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway.
21646473Cancer Res.2011Benzaïd I et al.High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.
19656068J. Infect. Dis.2009Qin G et al.Phosphoantigen-expanded human gammadelta T cells display potent cytotoxicity against monocyte-derived macrophages infected with human and avian influenza viruses.
19875454J. Biol. Chem.2010Mitrofan LM et al.Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells.
17693564Appl. Environ. Microbiol.2007Withers ST et al.Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity.
16698791J. Biol. Chem.2006Kavanagh KL et al.The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.
16179378Blood2006Thompson K et al.Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway.